Senior Scientist I, Host Cell Engineering

AbbVie

Confirmed live yesterday High trust
Hybrid

Quick summary

Work type
Hybrid
Location
Worcester, MA
Salary
$96,500–$183,500 / yr
Posted
64 days ago
Freshness
Confirmed live yesterday
Closes
Jul 9, 2126

Market check

Salary context

Below market

How this pay compares to similar roles

Similar $200k
This role $140k
$79k most similar roles pay here $259k

This role pays less than 85% of similar roles. Most pay $159,000–$241,750 — the shaded band above. At the midpoint, this role pays about $140k versus about $200k for comparable roles.

Based on 240 similar postings.

Employer

About AbbVie

AbbVie is a global biopharmaceutical company focused on discovering and delivering innovative medicines and solutions in immunology, oncology, neuroscience, and eye care. Its products include Humira, Skyrizi, and Rinvoq.

AbbVie currently has 297 open roles on FindRole.

Listed pay typically runs $109,500–$208,500 across 271 roles with salary data.

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View all roles at AbbVie

At a glance

TL;DR · Senior Scientist I, Host Cell Engineering

Senior Scientist I, Host Cell Engineering joins a multidisciplinary team focused on developing robust production cell lines for a clinical and commercial biologics pipeline. This lab-based role involves engineering next-generation mammalian host cells, specifically CHO cells, to enhance recombinant protein productivity, improve product quality, and streamline process efficiency. The successful candidate will perform genetic engineering, characterization of host and production cell lines, and collaborate with cross-functional teams including analytical and purification colleagues. Key technical competencies include experience with CRISPR-Cas9, Cas-Clover, NGS, Omics, bioinformatics, systems biology, artificial intelligence, machine learning, and high-throughput automation. The role requires expertise in cell and molecular biology, aseptic technique, flow cytometry, and fluorescence activated cell sorting to solve complex problems within the biologics production space. Candidates must be able to manage multiple projects while authoring technical reports and presenting data to leadership.

What you'll do

  • Execute genetic engineering and characterization of CHO host and production cell lines.
  • Optimize processes to improve recombinant protein productivity and product quality.
  • Implement advanced technologies like CRISPR-Cas9, NGS, and AI to accelerate biological programs.
  • Conduct independent laboratory research while troubleshooting experimental designs and equipment.
  • Author technical reports and present data findings to leadership and project teams.
  • Manage multiple projects across various therapeutic disciplines in a fast-paced environment.

What we're looking for

  • Bachelor’s degree with 10 years of experience, Master’s degree with 8 years of experience, or PhD with 0-2 years of experience in a scientific field.
  • Strong background in cell and molecular biology with extensive experience in cell culture and aseptic technique.
  • Experience with 'omics, genetic engineering, flow cytometry, FACS, NGS, expression vector design, bioinformatics, systems biology, ML, AI, or modeling (preferred).
  • Excellent problem-solving skills including critical and analytical thinking.
  • Excellent communication, leadership, and project management skills.
  • Demonstrated scientific writing and verbal communication skills.
  • Ability to independently design and execute experiments, interpret data, and identify follow-up strategies.
  • Proven track record of teamwork, adaptability, innovation, initiative, and integrity.

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