Senior Scientist I, Cell Culture Process Development

What you'll do

• Develop and characterize high-productivity CHO cell culture processes for cGMP biotherapeutic manufacturing.
• Execute technical transfer and provide ongoing manufacturing support for therapeutic proteins.
• Lead R&D initiatives to reduce cost of goods through improved platform processes and workflows.
• Implement advanced technologies including cell metabolic modeling, perfusion systems, and Process Analytical Technology (PAT) tools.
• Design and analyze cell culture experiments using Design of Experiments (DOE) principles.
• Author technical reports, protocols, and other key documentation for internal and external audiences.
• Troubleshoot technical issues and provide subject matter expertise for the production of commercial biologics.

What we're looking for

• Bachelor’s degree with 10 years of experience, Master’s degree with 8 years of experience, or a PhD in chemical engineering, biochemical engineering, or a related field.
• Proven ability to independently design experiments, troubleshoot technical issues, and deliver high-quality scientific output.
• Strong understanding of cell biology with extensive hands-on experience with mammalian suspension cell culture.
• Theoretical and practical knowledge to carry out the job functions.
• Understanding of cell culture processes including development, scale up/down, recombinant protein production, and protein characterization (preferred).
• Demonstrated experience in cell metabolic modeling and process modeling using mechanistic models or machine learning algorithms (preferred).
• Familiarity with bioreactor perfusion processes (preferred).
• Experience applying Process Analytical Technology (PAT) to improve cell culture processes (preferred).