This role pays more than
66%
of similar roles. Most pay
$150,000–$204,887
— the shaded band above.
At the midpoint, this role pays about
$189k
versus about
$177k
for comparable roles.
Based on 240 similar postings.
Employer
About Amgen
Amgen is a leading biotechnology company that discovers, develops, manufactures, and delivers innovative human therapeutics, with products addressing conditions such as anemia, bone loss, inflammation, and cancer. Industry: Biotechnology & Pharmaceuticals
Amgen currently has
46 open roles
on FindRole.
Listed pay typically runs
$136,906–$184,235
across 44 roles with salary data.
Principal Manufacturing Systems Engineer
As part of the drug substance manufacturing team, the Principal Manufacturing Systems Engineer manages a diverse portfolio of IS and automation projects within a technologically advanced facility featuring Industry 4.0 capabilities. The role involves performing cross-system assessments, conducting feasibility analyses, and translating strategic opportunities into executable plans while managing risks, resources, and budgets. Key responsibilities include analyzing business needs to create functional designs and coordinating with internal partners and vendors. Candidates must possess expertise in the Emerson Delta V Platform, Rockwell FactoryTalk, Rockwell PLCs, and Aveva PI Data Historian. Preferred skills include experience with Korber MES, Kneat platform documentation, GAMP software development lifecycles, ANSI/ISA-S88 and S95 standards, and 21 CFR Part 11 compliance. The role addresses complex manufacturing challenges by integrating advanced technologies like PAT, APC, IIoT, and cyber security principles into production environments.
Remote (Thousand Oaks, CA)42 days ago
$136,906–$185,227
DeltaV
Rockwell Automation
PLC
SCADA
HMI
Virtual Server
OPC
Profibus
DeviceNet
21 CFR Part 11
ASTM 2500
S88
S95
GAMP
Data Integrity
Project Management
Process Control Systems
Emerson DeltaV
DCS
OPC
Foundation Fieldbus
Profibus
Process Control Systems
Virtual Infrastructure
21 CFR Part 11
ASTM 2500
S88
S95
GAMP
GMP
GDP
Capital Project Lifecycle Management
Commissioning and Qualification
Technical Writing
PLC
SCADA
HMI
Ladder Logic
Machine Vision
Robotics
Data Historian
ERP
MES
Track and Trace
21 CFR Part 11
Computerized Systems Validation
Automation
AI
Machine Learning
RFID
Serialization
OT Systems
PLC
SCADA
HMI
Ladder Logic
Machine Vision
Robotics
Data Historian
Track and Trace
Serialization
21 CFR Part 11
MES
ERP
AI
Machine Learning
OT Systems
Commissioning and Qualification
Computerized Systems Validation
RFID