Senior Principal Scientist

What you'll do

• Define and lead analytical control strategies for multiple vaccine programs based on product quality attributes and risk profiles.
• Manage a team of scientists by providing direction, prioritization, coaching, and performance support.
• Lead the development, optimization, qualification, and lifecycle management of separation-based, spectroscopic, and mass spectrometry methods.
• Resolve complex and ambiguous analytical challenges using mechanistic understanding, experimental design, and cross-disciplinary input.
• Represent Analytical Development on cross-functional teams to communicate risks and data-driven recommendations to leadership.
• Drive innovation in analytical technologies, including AI, automation, and digital tools to improve throughput and decision quality.
• Direct the authoring and technical review of analytical methods, protocols, reports, and regulatory content.
• Forecast resource needs and coordinate matrixed contributions to ensure high-quality data delivery under strict quality standards.

What we're looking for

• PhD with at least 8 years of experience in analytical chemistry, biochemistry, pharmaceutical sciences, or a related discipline.
• Advanced expertise in analytical method development and characterization of biologics, vaccines, or complex modalities.
• Demonstrated experience managing and leading scientific teams through coaching, prioritization, and professional guidance.
• Extensive hands-on leadership experience with separation-based techniques such as liquid chromatography or capillary electrophoresis.
• Proven ability to lead method development, qualification, transfer, and technical documentation across multiple programs.
• Strong skills in scientific writing, data interpretation, project prioritization, and stakeholder management.
• Must have permanent work authorization to be employed in the United States.
• Knowledge of critical quality attributes for mRNA or protein products; experience with LC-MS or automation (preferred).