below marketmost similar roles pay hereabove market
This role pays more than
75%
of similar roles. Most pay
$187,665–$287,681
— the blue band above.
At the midpoint, this role pays about
$279k
versus about
$238k
for comparable roles.
Based on 240 similar postings.
Employer
About Bristol Myers Squibb
Bristol Myers Squibb is a global biopharmaceutical company committed to discovering, developing and delivering innovative medicines to patients.
Bristol Myers Squibb currently has
34 open roles
on FindRole.
Listed pay typically runs
$153,830–$186,404
across 26 roles with salary data.
JOB TITLE: Senior Director (QSP), Clinical Pharmacology & Pharmacometrics, Research Business Insights/Information Technology
The Senior Director (QSP), Clinical Pharmacology & Pharmacometrics, Research Business Insights/Information Technology leads a team of scientific technologists, product leaders, and specialized engineers. This leader serves as the primary point of accountability for the Clinical Pharmacology and Pharmacometrics technology stack, providing a scalable application and workflow backbone for Research and Development. Key responsibilities include delivering modeling environments, workflow automation, and governed operational capabilities to support quantitative preclinical-to-clinical bridging, dose selection, and regulatory evidence generation. The role requires expertise in population PK, PK/PD, PBPK, and QSP modeling. Candidates must utilize Quarto-based reporting automation, AI-enabled analytics, and advanced automation to improve reproducibility and inspection-readiness. This position solves the technical challenge of scaling complex quantitative pharmacology workflows while ensuring audit trails and data integrity for regulatory submissions.
Serve as the primary point of accountability for Clinical Pharmacology and Pharmacometrics (CPP) technology, applications, and workflows.
Own the modeling environments, reporting workflows, and operational support for core CPP use cases.
Lead the automation of priority CPP workflows, including model execution, simulation, and evidence reuse.
Ensure operational excellence, reliability, and governance across clinical PK/PD systems and reporting applications.
Support quantitative regulatory deliverables through the development of reproducible workflows and inspection-ready practices.
Partner with R&D data and lab teams to integrate CPP workflows with broader scientific and operational capabilities.
Lead and grow a specialized team of scientific technologists, product leaders, and engineers.
What we're looking for
Ph.D. in Pharmacometrics, Clinical Pharmacology, Pharmaceutical Sciences, Biostatistics, or a related quantitative field.
12+ years of experience in pharmaceutical R&D with deep clinical pharmacology, pharmacometrics, and model-informed drug development experience.
Proven experience implementing or leading CPP applications, PBPK and QSP environments, clinical PK/PD systems, or quantitative workflow automation.
Demonstrated experience supporting regulatory submissions, quantitative reporting, and governed workflows in Development-facing settings.
Director or Senior Director-level leadership experience; experience building and scaling a specialized scientific technology team is a strong differentiator.
Experience applying AI/ML or advanced automation to quantitative modeling, reporting, or regulated scientific workflows is preferred.
Experience as a clinical pharmacology or pharmacometrics technology leader inside a top-tier pharmaceutical R&D organization (preferred).
Track record of platforms that improved dose selection, quantitative decision-making, or regulatory execution in Development-facing settings (preferred).
GenAI
Predictive AI
In silico DMPK
Histopathology Image AI
Data Flows
Bioinformatics
Pharmacology
Toxicology
ADME
PK/PD
Clinical Pharmacology
GLP
IACUC
SAS
Pharmacometrics
Pharmacokinetics
Population PK
Population PK/PD
CDISC
Statistical Programming
Exposure-Response
Immunogenicity
Regulatory Submissions
Quality Control
South San Francisco, CA79 days ago
$185,200–$343,900
Biostatistics
Statistics
Data Science
Statistical Computing
Advanced Modeling
AI
ML
Real-World Data
Predictive Biomarkers
Simulation Frameworks
Quantitative Frameworks
Clinical Trial Research
Open Source Software
Applied AI
LLMs
RAG
MLOps
LLMOps
Agentic Systems
CI/CD
Infrastructure as Code
Knowledge Graphs
Semantic Search
Multimodal AI
Distributed Systems
APIs
Cloud Services
Observability
Data Contracts
MCP
A2A
Causal Inference