Principal Applied Threat Intelligence Manager
Microsoft
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AstraZeneca is a global biopharmaceutical company focused on the research, development, and commercialization of prescription medicines in oncology, cardiovascular, respiratory, and rare disease areas. Industry: Biopharmaceuticals
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The Director of Cyber Threat Intelligence leads a highly technical CTI function within the Cybersecurity Operations division to protect manufacturing, clinical trial platforms, and R&D environments. You will manage a team of analysts to deliver strategic, operational, and tactical intelligence that reduces enterprise risk by partnering with Vulnerability Management, Detection Engineering, and Incident Response teams. Key responsibilities include developing adversary prioritization frameworks, modeling attack paths across IT-to-OT pivots, performing structured threat actor attribution using the Diamond Model, and monitoring dark web forums for credential leaks or infrastructure overlaps. You will utilize tools including TIP, SIEM, EDR, and Sigma/KQL/SPL to automate enrichment and develop detections-as-code. The role requires expertise in MITRE ATT&CK (Enterprise/ICS) and specialized knowledge of pharmaceutical manufacturing continuity, clinical data integrity, and R&D intellectual property protection within a complex global infrastructure.
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