Vice President, Applied AI & Architecture

Pfizer

Confirmed live yesterday High trust
Closes in 4 days Hybrid

Quick summary

Work type
Hybrid
Location
New York City, NYCambridge, MACollegeville, PA
Salary
$274,000–$456,600 / yr
Employment
Full-time
Posted
3 days ago
Freshness
Confirmed live yesterday
Closes
Oct 15, 2026 (soon)

Market check

Salary context

Above market

How this pay compares to similar roles

Similar $210k
This role $365k
$113k $493k
below market most similar roles pay here above market

This role pays more than 99% of similar roles. Most pay $161,250–$258,000 — the blue band above. At the midpoint, this role pays about $365k versus about $210k for comparable roles.

Based on 240 similar postings.

Employer

About Pfizer

Pfizer Inc. is one of the world''s largest biopharmaceutical companies, researching, developing, manufacturing, and marketing medicines and vaccines across multiple therapeutic areas including oncology, cardiology, and infectious diseases. Industry: Biopharmaceuticals

Pfizer currently has 5 open roles on FindRole.

Most-posted roles

View all roles at Pfizer

At a glance

TL;DR · Vice President, Applied AI & Architecture

The Vice President, Applied AI & Architecture - US Commercial leads the technical vision for integrating artificial intelligence across the commercial organization. This senior leadership role involves defining the applied AI strategy, establishing architectural patterns, and creating technical decision frameworks to ensure scalable, secure, and reusable solutions. You will build a team of senior architects and engineers to translate business transformation priorities into technical roadmaps. Key responsibilities include overseeing generative AI, agentic systems, machine learning, retrieval architectures, evaluation, and observability. You will work with data, product, and engineering leaders to align AI capabilities with commercial data and workflows. The role solves the challenge of technical fragmentation by ensuring AI investments are integrated into a coherent enterprise architecture while maintaining responsible AI standards for privacy, security, and regulatory compliance.

What you'll do

  • Define and evolve the applied AI strategy and technical roadmap to support commercial priorities.
  • Design the target architecture connecting AI capabilities, commercial data, enterprise platforms, and user workflows.
  • Establish architectural patterns and standards for scalable, secure, and reusable AI solutions.
  • Create frameworks for evaluating AI use cases, technologies, vendors, and build-vs-buy decisions.
  • Provide technical oversight and design reviews for major AI initiatives to ensure feasibility and alignment.
  • Drive the reuse of common AI components and services to prevent technical duplication across the portfolio.
  • Embed responsible AI principles, including privacy, security, and human oversight, into all solution designs.
  • Build and lead a team of senior applied AI architects and technical experts.

What we're looking for

  • 15+ years of experience in AI, machine learning, data, enterprise architecture, software engineering, or technology strategy.
  • Significant senior leadership experience shaping technical direction across a large, complex, and matrixed organization.
  • Deep expertise in applied AI, including generative AI, agentic systems, machine learning, retrieval architectures, evaluation, and observability.
  • Proven experience defining enterprise or domain-level AI strategies and target architectures.
  • Demonstrated success translating complex business transformation priorities into technical strategies, roadmaps, and solution designs.
  • Experience establishing architecture standards, technical decision frameworks, and governance across multiple teams or business domains.
  • Strong understanding of enterprise data, cloud, platform, application, integration, cybersecurity, and software-engineering considerations.
  • Work authorization in the United States.

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