This role pays more than
57%
of similar roles. Most pay
$164,468–$255,193
— the shaded band above.
At the midpoint, this role pays about
$223k
versus about
$210k
for comparable roles.
Based on 240 similar postings.
Employer
About MSD
MSD (Merck Sharp & Dohme) is the international name for Merck & Co., a major U.S.-based pharmaceutical company.
MSD currently has
24 open roles
on FindRole.
Listed pay typically runs
$117,000–$184,200
across 24 roles with salary data.
Principal Scientist/Director (Downstream), Biologics Drug Substance Commercialization (BDSC) serves as a senior scientific and people leadership role within the BDSC-Downstream team. This position focuses on downstream processing for late-stage clinical and commercial biologics programs, including complex modalities like multi-specific antibody therapeutics. The individual will lead drug substance teams, manage a group of scientists, and provide technical leadership for laboratory and manufacturing scale studies involving process characterization, validation, and investigation. Key responsibilities include overseeing technology transfers to internal and external sites, authoring regulatory documentation, and managing lifecycle activities for commercial processes. Required expertise includes downstream unit operations such as preparative chromatography, tangential flow filtration, and virus retentive filtration. The role requires proficiency in chemical or biological engineering to solve complex manufacturing challenges while ensuring compliance with cGMP standards and U.S./EU regulatory expectations during the transition from development to global production.
Remote (West Point, PA)12 days ago
$173,200–$272,600
Bioprocess Engineering
Upstream Cell Culture
Process Development
Technology Transfer
cGMP
Process Characterization
Scale-up
Validation
Antibody Therapeutics
Viral Clearance
Process Performance Qualification (PPQ)
Analytical Characterization
Product Development Lifecycle
Clinical Manufacturing
Remote (West Point, PA)11 days ago
$117,000–$184,200
Biologics
Cell Culture
cGMP
Process Development
Upstream Processing
Design of Experiments (DOE)
Technology Transfer
Mammalian Cell Culture
Chromatographic Techniques
Quality by Design (QbD)
Lean Six Sigma
Regulatory Submissions
IND
MAA
BLA
Statistical Data Analysis
Remote (West Point, PA)+112 days ago
$117,000–$184,200
Bioprocess Engineering
cGMP
Design of Experiments (DOE)
Process Development
process scale up
Technology Transfer
Chromatographic Techniques
Bioreactors
Process Validation
Technical Writing
GMP
Downstream Processing
Single-Use Systems
DeltaV
MES
SAP
Veeva Quality Docs
JMP
Microsoft Office
Lean Manufacturing
Root Cause Analysis
Process Engineering
Equipment Qualification
Data Analysis
Project Management