Principal Scientist, Data Science, AI & Generative AI Systems

Johnson & Johnson

Confirmed live today High trust
Closes in 3 days Hybrid

Quick summary

Work type
Hybrid
Location
Spring House, PAMalvern, PA
Salary
$117,000–$201,250 / yr
Employment
Full-time
Posted
11 days ago
Freshness
Confirmed live today
Closes
Oct 30, 2026 (soon)

Market check

Salary context

Below market

How this pay compares to similar roles

Similar $185k
This role $159k
$104k $238k
below market most similar roles pay here above market

This role pays less than 71% of similar roles. Most pay $149,525–$220,000 — the blue band above. At the midpoint, this role pays about $159k versus about $185k for comparable roles.

Based on 240 similar postings.

Employer

About Johnson & Johnson

Johnson & Johnson is a multinational corporation operating in three main segments: consumer health products, pharmaceuticals, and medical devices, known for brands like Tylenol, Band-Aid, and Janssen. Industry: Pharmaceuticals & Medical Devices

Johnson & Johnson currently has 46 open roles on FindRole.

Listed pay typically runs $113,000–$201,250 across 38 roles with salary data.

Most-posted roles

View all roles at Johnson & Johnson

At a glance

TL;DR · Principal Scientist, Data Science, AI & Generative AI Systems

JOB TITLE: Principal Scientist, Data Science – AI & Generative AI Systems – R&D DDSAI – Therapeutics Development & Supply (TDS) The R&D Data Science organization is seeking a Principal Scientist, Data Science to design, build, evaluate, and deploy AI and generative AI systems within the Therapeutics Development & Supply domain. This hands-on individual contributor will develop LLM applications, agentic workflows, and AI-driven automation solutions to accelerate scientific, regulatory, and technical workflows. Key responsibilities include building systems for document authoring, knowledge retrieval, and evidence synthesis while ensuring responsible AI practices and technical rigor. The role requires proficiency in Python and experience with large language models, retrieval-augmented generation, embeddings, and vector databases. Candidates should possess a background in pharmaceutical CMC development and experience with open-source agentic frameworks like LangGraph or DSPy to solve complex problems in regulated GxP environments.

What you'll do

  • Design, build, test, and deploy AI and generative AI systems for documentation, knowledge retrieval, and decision support.
  • Build agentic AI workflows to coordinate models, tools, and data across multi-step scientific and supply chain processes.
  • Develop reusable AI capabilities that align with established architecture, platform standards, and scalable deployment practices.
  • Establish evaluation frameworks for LLM systems including rubrics for traceability, robustness, uncertainty, and usability.
  • Apply responsible AI practices such as human-in-the-loop validation, risk assessment, and content safety governance.
  • Maintain software engineering standards including modular design, testing, documentation, and lifecycle management.
  • Partner with regulatory, quality, and scientific stakeholders to define use cases and drive adoption of AI solutions.
  • Communicate system behaviors, risks, and technical tradeoffs to both technical and non-technical stakeholders.

What we're looking for

  • Degree in Engineering, Data Science, Life Sciences, Computer Science, or related field.
  • Advanced degree preferred.
  • 3–5+ years of hands-on experience building and deploying AI, NLP, or generative AI solutions, including large language models (LLMs).
  • Experience in Pharmaceutical Product Development, including Chemistry, Manufacturing and Controls (CMC).
  • Strong proficiency in Python.
  • Strong communication skills to explain technical topics to non-technical stakeholders.
  • Experience with open-source agentic frameworks (e.g., LangGraph, DSPy, mem0, etc.) (preferred).
  • Experience with retrieval-augmented generation, embeddings, vector databases, and model evaluation (preferred).

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