Principal Product Leader, Therapeutics Discovery

Genentech

Confirmed live today High trust

Quick summary

Work type
On-site
Location
South San Francisco, CA
Salary
$148,600–$276,000 / yr
Employment
Full-time
Posted
60 days ago
Freshness
Confirmed live today

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Salary context

Competitive pay

How this pay compares to similar roles

Similar $221k
This role $212k
$133k $291k
below market most similar roles pay here above market

This role pays less than 51% of similar roles. Most pay $189,400–$252,500 — the blue band above. At the midpoint, this role pays about $212k versus about $221k for comparable roles.

Based on 240 similar postings.

Employer

About Genentech

Genentech is a leading research-driven company dedicated to discovering and developing, manufacturing, and commercializing medicines for people with serious and life-threatening diseases.

Genentech currently has 36 open roles on FindRole.

Listed pay typically runs $146,000–$271,100 across 18 roles with salary data.

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At a glance

TL;DR · Principal Product Leader, Therapeutics Discovery

The Principal Product Leader- Therapeutics Discovery joins the Data and Digital Catalysts department within the Computational Sciences Center of Excellence. Reporting to the Domain Head for Therapeutics Discovery, this role involves defining and executing the strategy for a product family essential for making and testing molecules. The individual will manage the data lifecycle, provide data products for AI/ML and scientific analysis, and develop strategic roadmaps to support multiple therapeutic modalities. Key responsibilities include articulating product visions, managing stakeholder relationships, and documenting software requirements for custom and Commercial-Off-The-Shelf systems. The role requires expertise in the design-make-test-learn aspects of biotechnology, specifically regarding antibody engineering, medicinal chemistry, and automation. This position bridges wet and dry labs to create a computational ecosystem that accelerates drug discovery and decision-making.

What you'll do

  • Define the strategy and product vision for a product family within the Therapeutics Discovery Domain.
  • Develop a strategic product roadmap that aligns with scientific outcomes and drug discovery goals.
  • Manage the data lifecycle and provide data products to support AI/ML and scientific analysis.
  • Document detailed software requirements, user stories, and business processes for custom and COTS systems.
  • Advocate for future-facing solutions and influence the broader informatics ecosystem.
  • Oversee budget projections and coordinate with implementation teams to drive product delivery.
  • Lead the consolidation and deprecation of legacy systems to reduce technical debt.
  • Cultivate internal and external partnerships with scientific collaborators and technical teams.

What we're looking for

  • Bachelor’s degree plus at least 7 years, or an advanced degree plus at least 2 years of proven experience leading delivery of impactful internal solutions.
  • Experience working in a biotechnology setting and understanding scientific drug discovery processes.
  • Strong skills in Product Management, including product vision definition, strategic thinking, and extended stakeholder management.
  • Hands-on domain expertise in the design-make-test-learn aspects of biotechnology.
  • Understanding of how scientific data is collected, managed, analyzed, and used in the discovery process.
  • Experience documenting detailed software requirements, user stories, business processes, and software specifications for custom and COTS systems.
  • Demonstrated ability to build positive relationships and work with globally distributed and cross-functional teams.
  • Outstanding oral and written two-way communication skills to articulate vision and strategy to diverse audiences.

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