Principal Data Scientist

Genentech

Confirmed live yesterday High trust
Hybrid

Quick summary

Work type
Hybrid
Location
South San Francisco, CA
Employment
Full-time
Posted
2 days ago
Freshness
Confirmed live yesterday

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How this pay compares to similar roles

Similar $179k
$114k $237k
below market most similar roles pay here above market

This listing doesn't post a salary. Most similar roles pay $149,856–$208,800.

Based on 240 similar postings.

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About Genentech

Genentech is a leading research-driven company dedicated to discovering and developing, manufacturing, and commercializing medicines for people with serious and life-threatening diseases.

Genentech currently has 39 open roles on FindRole.

Listed pay typically runs $143,050–$265,550 across 20 roles with salary data.

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At a glance

TL;DR · Principal Data Scientist

The Principal Data Scientist joins the Data Science and Machine Learning team as a technical leader and domain authority for advanced experimentation and measurement solutions. This individual-contributor role involves driving the technical design and industrialization of enterprise-grade causal AI and statistical models to measure business impact and optimize resource allocation. Key responsibilities include building production-grade models for A/B testing, quasi-experimentation, Media/Marketing Mix Modeling, synthetic controls, uplift modeling, and non-parametric measurement. The candidate will utilize Python, R, SQL, PyTorch, TensorFlow, scikit-learn, statsmodels, CausalML, DoWhy, and EconML, while scaling algorithms using Spark, Databricks, Hadoop, and cloud platforms like AWS, GCP, or Azure. The work focuses on quantifying the causal impact of promotional activities and integrating Bayesian modeling and Generative AI into measurement ecosystems.

What does a Data Scientist earn in California?

Median $214500 from 115 postings across 26 companies.

See salary data

What you'll do

  • Design and develop production-grade statistical, econometric, and causal inference models including A/B testing and Marketing Mix Modeling.
  • Translate complex business objectives into robust mathematical frameworks and scalable technical requirements for Causal AI applications.
  • Build scalable algorithms to quantify the causal impact of promotional activities and generate business optimization recommendations.
  • Lead the end-to-end industrialization of Causal AI solutions by partnering with data engineers, MLOps, and commercial stakeholders.
  • Serve as a technical authority by performing code reviews, providing design guidance, and mentoring senior and junior data scientists.
  • Communicate complex causal modeling concepts into clear, actionable narratives for both technical teams and non-technical business leaders.
  • Research and integrate academic advancements in Causal ML, Bayesian modeling, and Generative AI into the measurement ecosystem.

What we're looking for

  • A Bachelor’s Degree and 8+ years of work experience, or an equivalent mix of education and work experience, is required.
  • 8+ years of relevant industry experience in Data Science, Applied Statistics, or ML engineering is required.
  • 5+ years of hands-on specialization in Causal Inference, Experimental Design, Measurement, and Optimization is required.
  • Expert-level knowledge of open-source frameworks for ML, statistics, and causal inference is required.
  • Advanced proficiency in Python and/or R, along with strong SQL skills, is required.
  • Hands-on experience scaling algorithms using big data environments and cloud platforms is required.
  • An advanced degree (MS or PhD) in a quantitative field with 6+ years of relevant experience is preferred.
  • Experience with large-scale datasets in healthcare, pharmaceuticals, or regulated environments is preferred.

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