Director, Physical AI for Autonomous Discovery

Johnson & Johnson

Confirmed live today High trust
Hybrid

Quick summary

Work type
Hybrid
Location
Spring House, PACambridge, MA
Salary
$164,000–$282,900 / yr
Employment
Full-time
Posted
11 days ago
Freshness
Confirmed live today

Market check

Salary context

Below market

How this pay compares to similar roles

Similar $246k
This role $223k
$149k $308k
below market most similar roles pay here above market

This role pays less than 67% of similar roles. Most pay $208,845–$282,275 — the blue band above. At the midpoint, this role pays about $223k versus about $246k for comparable roles.

Based on 240 similar postings.

Employer

About Johnson & Johnson

Johnson & Johnson is a multinational corporation operating in three main segments: consumer health products, pharmaceuticals, and medical devices, known for brands like Tylenol, Band-Aid, and Janssen. Industry: Pharmaceuticals & Medical Devices

Johnson & Johnson currently has 46 open roles on FindRole.

Listed pay typically runs $113,000–$201,250 across 38 roles with salary data.

Most-posted roles

View all roles at Johnson & Johnson

At a glance

TL;DR · Director, Physical AI for Autonomous Discovery

The Director, Physical AI for Autonomous Discovery joins the In Silico Drug Discovery team to lead a focused group developing models for autonomous laboratory experimentation. This leader will define the Physical AI strategy, building systems that perceive, reason, and act within laboratory environments. Key responsibilities include developing AI models for instrument reasoning, adaptive experimental optimization, and physical error detection. The role involves creating agentic systems to coordinate Design-Make-Test-Analyze cycles and deploying closed-loop learning in real laboratory settings. Required expertise includes Physical AI, world models, reinforcement learning, Bayesian optimization, and robotics. Candidates must possess skills in Python, machine learning frameworks, and laboratory automation, including liquid handling and machine vision. This position solves the challenge of creating self-improving discovery workflows to improve experimental quality, throughput, and reproducibility in drug discovery.

What you'll do

  • Define and execute the Physical AI strategy and roadmap for autonomous laboratory experimentation.
  • Lead a high-performing team to develop models that perceive, reason, and act within laboratory environments.
  • Build AI models to understand instruments, samples, reagents, robotic systems, and overall laboratory states.
  • Develop adaptive experimental optimization capabilities using active learning, Bayesian optimization, and reinforcement learning.
  • Create systems for physical error detection, root-cause assessment, and automated workflow replanning.
  • Design agentic and multi-agent systems to coordinate experiment planning, execution, and data interpretation.
  • Partner with engineering and discovery science teams to deploy reliable closed-loop learning in real laboratories.
  • Embed uncertainty calibration, safety constraints, and governance into autonomous decision-making processes.

What we're looking for

  • PhD in artificial intelligence, machine learning, robotics, computer science, engineering, computational biology, or a related quantitative field.
  • Demonstrated experience developing AI systems that operate in physical or scientific environments.
  • Deep expertise in world models, reinforcement learning, Bayesian optimization, causal inference, multimodal AI, robotics, or scientific machine learning.
  • Strong software-development skills including Python and modern machine-learning frameworks.
  • Ability to translate scientific and operational requirements into robust, scalable AI models and communicate across multidisciplinary teams.
  • Strong collaboration skills to work in a matrix environment.
  • Experience with self-driving laboratories, laboratory automation, or closed-loop scientific experimentation (preferred).
  • Experience with vision-language-action models, digital twins, machine vision, robotic control, or multi-agent systems (preferred).

More like this

Similar roles

Senior Principal Investigator, Physical AI for Autonomous Discovery

Johnson & Johnson

Spring House, PA +1 11 days ago $137,000–$235,750
Python Reinforcement Learning Bayesian Optimization Active Learning Multi-agent Systems Machine Learning Robotics MLOps Digital Twins Anomaly Detection Causal Inference APIs Data Pipelines Observability Laboratory Automation Machine Vision State Estimation Multimodal AI
Hybrid

Lead Physical AI Engineer

Caterpillar

Irving, TX 39 days ago $147,760–$240,110
NVIDIA Newton NVIDIA Isaac Sim OpenUSD Python C++ ROS2 Digital Twins Physical AI Reinforcement Learning Machine Dynamics Robotics Simulation Synthetic Data Generation Reduced Order Models (ROM Software-in-the-loop GitHub Copilot
8+ yrs exp

Director, Physical AI

Cisco

San Jose, CA 7 days ago $230,000–$290,800
ROS 2 Python C++ NVIDIA Isaac Sim TensorRT CUDA ONNX Runtime LiDAR SLAM Nav2 FreeRTOS CAN bus EtherCAT I2C SPI gRPC REST APIs LLMs 802.1X mTLS Duo Okta Sim2Real Gazebo MuJoCo Whisper OCR RFID NFC
10+ yrs exp Hybrid

Physical AI, Computer Vision Engineer

Amd

Austin, TX +2 112 days ago $174,400–$261,600
Embedded Linux RTOS Computer Vision AI Inference Heterogeneous Computing FPGA PyTorch TensorFlow ONNX ROS 2 Vitis™ AI OpenGL Vulkan Wayland Sensor Fusion Linux Kernel BSP

Robotics & Physical AI Architect

Oracle

31 days ago $157,500–$355,400
ROS 2 DDS MQTT OPC-UA VDA5050 OpenRMF Python C++ Go Java Rust Kubernetes Linux MLOps Isaac Sim Gazebo Zero Trust OTA Updates Distributed Systems Cloud-Native Reinforcement Learning Vision-Language-Action (VLA) Models Digital Twins
10+ yrs exp

Principal Architect, Reinforcement Learning (Physical AI)

Caterpillar

Irving, TX 4 days ago $147,760–$240,110
Reinforcement Learning Imitation Learning Python PyTorch C++ CUDA JAX Kubernetes Ray Slurm Isaac Lab Isaac Sim Omniverse MuJoCo Brax PPO SAC GRPO RLHF DPO Sim-to-Real CI/CD Digital Twins Edge Computing MPC Trajectory Optimization ISO 26262 SOTIF ISO 13849 Bazel
8+ yrs exp