Senior Scientist II, Pharmaceutical Development - Thermodynamics & AI/ML Applications

AbbVie

Confirmed live 2 days ago High trust

Quick summary

Work type
On-site
Location
Ludwigshafen, RP, Germany
Employment
Full-time
Posted
38 days ago
Freshness
Confirmed live 2 days ago
Closes
Aug 4, 2126

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Salary context

How this pay compares to similar roles

Similar $187k
$113k most similar roles pay here $237k

This listing doesn't post a salary. Most similar roles pay $152,150–$221,000.

Based on 240 similar postings.

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About AbbVie

AbbVie is a global biopharmaceutical company focused on discovering and delivering innovative medicines and solutions in immunology, oncology, neuroscience, and eye care. Its products include Humira, Skyrizi, and Rinvoq.

AbbVie currently has 297 open roles on FindRole.

Listed pay typically runs $109,500–$208,500 across 271 roles with salary data.

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At a glance

TL;DR · Senior Scientist II, Pharmaceutical Development - Thermodynamics & AI/ML Applications

As a Senior Scientist II, Pharmaceutical Development – Thermodynamics & AI/ML Applications, you will join a multidisciplinary team to design and implement thermodynamics-based and AI/ML-enabled solutions for pharmaceutical formulation and process development. You will be responsible for translating complex physicochemical and process data into predictive insights regarding solubility, phase behavior, physical stability, and material interactions. Your daily work involves building hybrid models that combine first-principles understanding with machine learning methods to ensure scientifically grounded results. You will develop in-silico digital tools and decision-support workflows to guide formulation selection and risk assessments. The role requires expertise in thermodynamics, quantum mechanical principles, and data science for physical systems. You will utilize AI/ML techniques to solve real-world development challenges while collaborating with laboratory scientists and modeling experts to ensure robust model validation and reproducible outcomes across various pharmaceutical programs.

What you'll do

  • Develop and apply predictive models to guide formulation and process development decisions across pharmaceutical programs.
  • Apply thermodynamic and quantum mechanical principles to predict material behaviors like solubility, phase behavior, and crystallization.
  • Build and improve models for physical stability, material compatibility, and excipient interactions of drug products.
  • Create hybrid tools that integrate mechanistic physics-based insights with machine learning and experimental data.
  • Execute robust model validation strategies including uncertainty assessment and applicability domain evaluation.
  • Convert complex physicochemical datasets into actionable insights for risk assessments and experiment prioritization.
  • Communicate technical findings, assumptions, and limitations clearly to both technical and non-technical stakeholders.

What we're looking for

  • PhD in pharmaceutical sciences, chemical engineering, physical chemistry, materials science, data science for physical systems, or related disciplines.
  • Strong understanding of thermodynamics and its application to pharmaceutical materials, formulations, and process performance.
  • Proven ability to perform quantitative modeling and analyze/interpret physicochemical experimental data.
  • Experience using AI/ML for scientific or engineering problems with a focus on data quality, model suitability, and interpretability.
  • Ability to combine mechanistic insight with data-driven methods to address real-world development challenges.
  • Proficiency in structuring analyses, documenting methods, and presenting conclusions in a business-relevant manner.
  • Strong collaboration and professional communication skills for working across cross-functional, technical, and international teams.
  • Excellent written and verbal communication skills in English.

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