As a Senior Principal Scientist in Process Chemistry at the CPAD group in Bothell, WA, you will lead technical teams in designing and executing complex laboratory experiments for route development, process optimization, and scale-up of novel small molecule components. You will apply modern synthetic organic chemistry principles and state-of-the-art technologies such as high-throughput experimentation (HTE) and continuous processing to develop scalable processes for both early and late-stage programs. Responsibilities include mentoring junior scientists, authoring patents and regulatory documents, and representing process chemistry in cross-functional project teams. The role requires a PhD in Organic Chemistry with 8+ years of industry experience or a Master’s degree with 15+ years of relevant experience, along with expertise in synthetic organic chemistry, reaction mechanisms, and GMP operations. Preferred qualifications include experience in developing drug-linkers for targeted therapeutics and mentoring scientific staff.
Skills
HTE
continuous processing
catalysis
predictive software
GMP
regulatory submissions
organic chemistry
reaction mechanisms
process development
purification technologies
analytical technologies
patents
peer-reviewed publications
cross-functional teams
technology transfer
regulated pharmaceutical environments
What you'll do
Lead teams in designing, executing, and interpreting complex laboratory experiments for route development.
Develop robust processes ensuring safety, scalability, and efficiency for both early and late-stage programs.
Author patents, publications, and regulatory documents to protect and communicate innovative processes.
Apply advanced synthetic chemistry principles and data-rich methods to accelerate process development cycles.
Mentor junior scientists and foster a collaborative environment focused on scientific rigor and innovation.
What we're looking for
PhD in Organic Chemistry with over 8 years of industry experience or Master’s degree with over 15 years in pharmaceutical process development.
Deep understanding of synthetic organic chemistry, reaction mechanisms, and modern purification technologies.
Proven scientific impact through peer-reviewed publications, patents, or conference presentations.
Strong communication skills and collaborative leadership in cross-functional teams.
Experience supporting drug development from preclinical to commercial stages.
Knowledge of GMP operations and authoring regulatory submissions in regulated environments.
Market check
Salary context
This
$124,400–$207,400
range sits above
43%
of similar postings on FindRole.
Peer median band
$129,050–$225,000
Median floor and ceiling across peers.
Typical midpoint (25–75%)
$150,478–$209,000
Middle half of comparable postings.
Based on 240 comparable postings.*
* 240 is the maximum number of comparable postings sampled.
Employer
About Pfizer
Pfizer Inc. is one of the world''s largest biopharmaceutical companies, researching, developing, manufacturing, and marketing medicines and vaccines across multiple therapeutic areas including oncology, cardiology, and infectious diseases. Industry: Biopharmaceuticals
Pfizer currently has
18 open roles
on FindRole.
Listed pay typically runs
$106,000–$176,600
across 18 roles with salary data.
Remote (Usa - New Jersey - Rahway, US)16 days ago
$117,000–$184,200
GMP
ICH
CMC
Project Management
Financial Forecasting
Risk Assessment
Analytical Method Development
Chromatography
Mass Spectrometry
PAT
Process Analytical Technology
Chemical Biology
Pharmaceutical Sciences
Flow Cytometry
Data-Driven Decision Making
Operational Excellence