Senior Manufacturing Systems Engineer – Manufacturing Systems and Integrated Technologies

Amgen

Remote

Quick summary

Work type
Remote
Location
Thousand Oaks, CA
Salary
$147,421–$177,467 / yr
Posted
72 days ago

Market check

Salary context

Competitive pay

How this pay compares to similar roles

Similar $166k
This role $162k
$131k most similar roles pay here $201k

This role pays less than 61% of similar roles. Most pay $138,187–$193,000 — the shaded band above. At the midpoint, this role pays about $162k versus about $166k for comparable roles.

Based on 240 similar postings.

Employer

About Amgen

Amgen is a leading biotechnology company that discovers, develops, manufactures, and delivers innovative human therapeutics, with products addressing conditions such as anemia, bone loss, inflammation, and cancer. Industry: Biotechnology & Pharmaceuticals

Amgen currently has 36 open roles on FindRole.

Listed pay typically runs $136,906–$177,467 across 35 roles with salary data.

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At a glance

TL;DR · Senior Manufacturing Systems Engineer – Manufacturing Systems and Integrated Technologies

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As a Senior Manufacturing Systems Engineer in Amgen’s Clinical and Commercial Manufacturing Operations Technology team, you will drive the operation, refinement, and integration of advanced manufacturing applications to ensure seamless product delivery. Your daily responsibilities include managing MES platforms, supporting key computerized systems like PI Data Historian and Instrument Data Acquisition (IDA), and collaborating with global stakeholders to standardize MES processes across all Amgen locations. You’ll work closely with cross-functional teams such as Manufacturing, Supply Chain, Quality, and Engineering to implement digital initiatives and ensure compliance with regulatory standards. Key skills include experience in biotech/pharmaceutical environments, database management, and strong analytical and troubleshooting abilities. This role demands proficiency in MES/IDA systems, GxP computer systems, and a solid understanding of Industry 4.0 technologies to enhance manufacturing efficiency and capacity.

Skills

MES PI_Data_Historian Instrument_Data_Acquisition CI/CD SQL CDOCS ALM Kubernetes Docker Terraform AWS Azure Git Jira Confluence Python PostgreSQL Industry_4.0 Cyber_Resiliency Sentinels ECR_Network

What you'll do

  • Manage key system integrations to streamline manufacturing operations.
  • Provide on-call support for operations technology application issues at the ATO site.
  • Lead major incident investigations and implement corrective actions.
  • Ensure compliance by maintaining inspection readiness for critical applications.
  • Support regulatory inspections by delivering presentations on site systems.
  • Introduce Industry 4.0 technologies to improve manufacturing efficiency.
  • Train team members to develop multi-system competencies and support operational excellence.

What we're looking for

  • 5+ years of experience in Information Systems or Systems Engineering.
  • Experience with GxP computer systems in a regulated environment.
  • Strong analytical and troubleshooting skills.
  • Database management skills including queries and stored procedures.
  • Leadership and collaboration skills for project management and process improvement.
  • Expertise in managing system integrations and supporting manufacturing operations technology.

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