Principal Scientist, Process Chemistry

Pfizer

Quick summary

Work type
On-site
Location
Bothell, WA
Salary
$106,000–$176,600 / yr
Posted
5 days ago
Closes
Jun 24, 2026
Nearby
99+ roles within 25 mi

Market check

Salary context

Below market

How this pay compares to similar roles

Similar $193k
This role $141k
$91k most similar roles pay here $243k

This role pays less than 85% of similar roles. Most pay $161,187–$224,267 — the shaded band above. At the midpoint, this role pays about $141k versus about $193k for comparable roles.

Based on 240 similar postings.

Employer

About Pfizer

Pfizer Inc. is one of the world''s largest biopharmaceutical companies, researching, developing, manufacturing, and marketing medicines and vaccines across multiple therapeutic areas including oncology, cardiology, and infectious diseases. Industry: Biopharmaceuticals

Pfizer currently has 33 open roles on FindRole.

Listed pay typically runs $124,400–$207,400 across 33 roles with salary data.

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View all roles at Pfizer

At a glance

TL;DR · Principal Scientist, Process Chemistry

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As a Principal Scientist in Pfizer’s Chemical Process and Analytical Development (CPAD) group based in Bothell, WA, you will lead a team of process chemists in developing chemical processes for novel drug-linkers used in antibody-drug conjugates. Your daily responsibilities include designing and executing complex laboratory experiments, employing advanced technologies like high-throughput experimentation and predictive software to accelerate development, and managing technology transfer to CDMOs. You will also mentor junior staff, communicate technical solutions to cross-functional teams, and maintain regulatory compliance throughout the drug development lifecycle from pre-clinical to commercialization. The role requires a PhD in Organic Chemistry with extensive experience in pharmaceutical process development, along with expertise in synthetic organic chemistry, analytical technologies, and GMP manufacturing. Experience with ADCs and mentoring scientific staff is preferred.

Skills

Python R MATLAB High-Throughput Experimentation Data-Rich Experimentation Computational Tools Predictive Software GMP CDMOs Regulatory Documents Patents Organic Chemistry Process Development Analytical Technologies PPE Safety Glasses Lab Coats Gloves

What you'll do

  • Design and execute complex laboratory experiments for drug-linker development.
  • Employ advanced technologies like high-throughput experimentation and predictive software in process development.
  • Lead technology transfer to CDMOs for GMP manufacturing of novel drug-linkers.
  • Author technical documents, patents, and scientific publications for external recognition.
  • Mentor junior staff and promote a supportive work environment within the team.
  • Drive strategic and technical aspects of early and late-phase pharmaceutical projects.

What we're looking for

  • PhD in Organic Chemistry with 4+ years of experience in pharmaceutical process development.
  • Proven track record of scientific innovation through authorship of peer-reviewed publications and patents.
  • In-depth knowledge of synthetic organic chemistry, process development, engineering, and analytical technologies.
  • Excellent communication skills for collaboration with stakeholders and cross-functional teams.
  • Experience in regulated pharmaceutical environments including GMP manufacturing and regulatory compliance.

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