As a Principal Manufacturing Systems Engineer at Amgen's North Carolina site, you will lead the delivery of IS/Automation projects by managing portfolios, resources, and risks while ensuring financial compliance. You will assess cross-system feasibility, prioritize work, and recommend optimal solutions, translating strategic opportunities into executable plans aligned with corporate standards. Your role involves resolving complex issues, managing relationships with stakeholders, and communicating effectively across organizational levels to propose actionable solutions. The ideal candidate has extensive experience in manufacturing process automation, particularly with Emerson Delta V Platform, Rockwell FactoryTalk, and Aveva PI Data Historian, along with knowledge of GAMP software development lifecycle and industry standards like ANSI/ISA-S88 and S95. This position demands expertise in PAT, APC, AR/VR, IIoT, and cyber security principles within a pharmaceutical or biotech setting.
Skills
Emerson Delta V
Rockwell FactoryTalk
Aveva PI Data Historian
Kneat
GAMP
ANSI/ISA-S88
IIoT
PAT
APC
AR/VR
Control Tower
21 CFR Part 11
PLC
Validation
Change Control
Cyber Security
MES
What you'll do
Own and manage the delivery of IS/Automation project portfolios with planning, risk management, and financial oversight.
Resolve complex technical and business issues across multiple projects using expertise in project management and technology.
Conduct cross-system assessments to prioritize work and recommend optimal solutions for manufacturing systems.
Translate strategic opportunities into executable plans aligned with corporate standards and local business needs.
Manage relationships with peers, IS service owners, business partners, enterprise IS services, and vendors effectively.
What we're looking for
Minimum 4 years of experience in Information Systems and Manufacturing Process automation.
Proven ability to manage multiple IS/Automation projects with portfolio planning and risk management.
Experience with Emerson Delta V Platform, Rockwell FactoryTalk, and Aveva PI Data Historian.
Knowledge of GAMP software development lifecycle and ANSI/ISA-S88 industry standards.
Strong project management skills and the ability to translate strategic opportunities into executable plans.
Demonstrated understanding of cyber security principles in manufacturing network operations.
Excellent interpersonal skills for effective collaboration with cross-functional teams.
Market check
Salary context
This
$160,327–$216,913
range sits above
58%
of similar postings on FindRole.
Peer median band
$140,000–$224,100
Median floor and ceiling across peers.
Typical midpoint (25–75%)
$151,275–$223,300
Middle half of comparable postings.
Based on 239 comparable postings.*
* 240 is the maximum number of comparable postings sampled.
Employer
About Amgen
Amgen is a leading biotechnology company that discovers, develops, manufactures, and delivers innovative human therapeutics, with products addressing conditions such as anemia, bone loss, inflammation, and cancer. Industry: Biotechnology & Pharmaceuticals
Amgen currently has
23 open roles
on FindRole.
Listed pay typically runs
$131,708–$173,047
across 22 roles with salary data.
Remote (Us - North Carolina - Holly Springs, US)85 days ago
$118,497–$134,250
DeltaV
Rockwell FactoryTalk
Building Automation Systems (BAS)
ThinManager
Siemens location tracking
SQL
Windows-based systems
virtualization
networking
storage
Active Directory
GMP software development lifecycle
change control
validation practices
Agile methodologies
Remote (Us - North Carolina - Holly Springs, US)21 days ago
$136,906–$185,227
Emerson DeltaV DCS
OPC
Foundation Fieldbus
Profibus
DeviceNet
DeltaV Live
Python
PLC programming
SCADA systems
Process Control Network design
Virtual infrastructure design
Automation system integration
Continuous improvement methodologies
Preventive maintenance
Corrective maintenance
System administration