Enterprise Architect, Pharma Commercial

Genentech

Confirmed live yesterday High trust

Quick summary

Work type
On-site
Location
South San Francisco, CA
Salary
$170,800–$317,200 / yr
Employment
Full-time
Posted
86 days ago
Freshness
Confirmed live yesterday

Market check

Salary context

Above market

How this pay compares to similar roles

Similar $207k
This role $244k
$131k most similar roles pay here $337k

This role pays more than 76% of similar roles. Most pay $174,656–$239,637 — the shaded band above. At the midpoint, this role pays about $244k versus about $207k for comparable roles.

Based on 240 similar postings.

Employer

About Genentech

Genentech is a leading research-driven company dedicated to discovering and developing, manufacturing, and commercializing medicines for people with serious and life-threatening diseases.

Genentech currently has 27 open roles on FindRole.

Listed pay typically runs $150,200–$279,000 across 19 roles with salary data.

Most-posted roles

View all roles at Genentech

At a glance

TL;DR · Enterprise Architect, Pharma Commercial

Enterprise Architect - Pharma Commercial serves as a strategic bridge between the Strategy, Portfolio & Governance organization and Pharma Medicines within a federated model. This role involves orchestrating the global architecture network to translate business goals into multi-year technology roadmaps across Market Access, Marketing, Customer Engagement, Analytics, and Commercial Operations. The architect will lead a network of embedded architects, establish technical guardrails, manage technical debt, and develop capability maps using ArchiMEDES (SAP LeanIX). Key responsibilities include modernizing customer engagement through AI-driven content supply chains and ensuring compliance with GDPR and HIPAA standards. Required expertise includes experience with Veeva, Salesforce, Master Data Management, and TOGAF frameworks. The role addresses the challenge of migrating legacy commercial systems to modern, cloud-native ecosystems while managing high-volume integrations between front- and back-office systems in a complex pharmaceutical environment.

What you'll do

  • Translate business goals into multi-year technology roadmaps across Market Access, Marketing, Customer Engagement, Analytics, and Commercial Operations.
  • Lead a federated network of architects to establish shared strategic priorities, technology guardrails, and security standards.
  • Drive architectural success for high-impact initiatives like customer engagement modernization and AI-driven content supply chains.
  • Develop and maintain commercial capability maps, target-state architectures, and technology inventories using ArchiMEDES.
  • Evaluate investment decisions by analyzing strategic impacts, platform reuse, and technical debt to optimize total cost of ownership.
  • Monitor emerging technologies and evaluate vendors to ensure a future-ready, optimized architecture.
  • Ensure all commercial architectures comply with global data privacy regulations and patient data governance standards.

What we're looking for

  • Bachelor’s degree in Engineering, IT, or Science.
  • Master’s degree (preferred).
  • At least 10 years of experience in IT and enterprise/domain architecture including migrating legacy systems to cloud-native ecosystems.
  • At least 5 years of experience in the biotech/pharma industry.
  • Deep domain expertise in global Pharma Commercial operations, including Field CRM, Omnichannel Marketing, Market Access, and Patient Services.
  • Expertise in modern digital tech stacks like Veeva and Salesforce, along with high-volume integrations and MDM.
  • Familiarity with enterprise architecture frameworks such as TOGAF and agile/product-led delivery methodologies.
  • Proven ability to lead networks of architects through influence rather than direct authority.

More like this

Similar roles

Enterprise Architect

Danaher Corporation

Sunnyvale, CA 136 days ago $190,000–$220,000
Enterprise Architecture Generative AI Security Identity and Access Management Encryption TOGAF ArchiMate UML SAP LeanIX Process Modeling Compliance
10+ yrs exp

Enterprise Architect

Booz Allen Hamilton

Arlington, VA 16 days ago $86,800–$198,000
Enterprise Architecture MBSE DoDAF API Databricks Tableau Qlik Palantir GovCloud NIST RMF FISMA System Integration Cybersecurity Portfolio Management Data Integration Infrastructure Design
5+ yrs exp

Enterprise Architect

General Dynamics

Falls Church, VA 30 days ago $119,000–$161,000
TOGAF DoWAF UML SysML Azure AWS M365 SharePoint ServiceNow Cameo MagicDraw Sparx EA Visio draw.io RMF Zero Trust ITIL CompTIA Security+
5+ yrs exp Hybrid

Senior Enterprise Architect

Cardinal Health

88 days ago $123,400–$176,300
Enterprise Architecture Google Cloud AWS Microsoft Azure RESTful APIs HTML JavaScript ETL ELT EAI IaaS PaaS SaaS TOGAF Zachman HIPAA GDPR
4+ yrs exp Hybrid

AVP Enterprise Architecture

Unum Group

Chattanooga, TN +2 31 days ago $133,500–$274,100
Enterprise Architecture ArchiMate BizzDesign Agile Lean Continuous Deployment Risk Assessment Change Management Configuration Management Value Stream Mapping Proof of Concept

Principal Domain Architect

McKesson Corporation

Irving, TX 20 days ago
Enterprise Architecture Cloud-native Hybrid-cloud API Microservices Distributed Systems Azure Power Platform SAP AI Generative AI Agentic AI LeanIX Ardoq Data Architecture Order Management
10+ yrs exp Hybrid