Senior Principal Scientist, Data Science RWE

What you'll do

• Lead a portfolio of Real-World Evidence (RWE) projects and mentor team members.
• Develop and maintain a common suite of tools to accelerate RWE project delivery.
• Manage end-to-end RWE studies including research conceptualization, study design, and data interpretation.
• Apply RWD methodologies to mitigate biases in external control arm and comparative effectiveness studies.
• Generate actionable insights from post-hoc RCT analyses and observational databases to support regulatory interactions.
• Create study protocols, statistical analysis plans, and programming deliverables like tables and figures.
• Partner with Therapeutic Area scientists to conceptualize and deliver Real World Evidence.

What we're looking for

• Ph.D. degree in epidemiology or biostatistics.
• Expert coding skills using R, Python, or SAS.
• At least 5 years of relevant experience within biopharma companies, RWE consulting firms, or other relevant healthcare industries.
• Extensive hands-on experience with data extraction, cleaning, analysis, and statistical methods to mitigate confounding and selection biases.
• Expertise with multiple real-world data sources including EHR, insurance claims, and registry data.
• Familiarity with clinical trial data structure.
• Excellent interpersonal, communication, and presentation skills.
• Familiarity with drug discovery, clinical development, oncology, immunology, neuroscience, or regulatory-grade evidence (preferred).