Our Purpose

Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.

Title and Summary

Senior Software Quality Engineer

Overview:
Mastercard’s Portfolio Intelligence team, part of the Services organization, is seeking a Senior Software Quality Engineer to hold a valued role within a rapidly growing and successful firm, working closely with experienced and driven engineers to solve problems as a team.
As part of the Portfolio Intelligence team, you will bring your testing skills to drive the quality of a transformational new platform for financial institutions, leveraging large data sets and providing actionable insights. We are looking for an innovative software quality engineer who can design and execute test plans for key full-stack features and thrive in a fast-paced, agile team. The range of work you encounter varies from writing automated tests to ensuring analytical accuracy and beyond. This individual will partner closely with the New Product Development organization to deliver a solution that drives value for our customers.
Engineers work in small, flexible teams. Every team member contributes to designing, building, and testing features. We take an agile approach to software development and practice continuous integration and delivery. The range of work that a team will encounter varies from front-end web development to writing server-side calculation code to database work. We prefer no rigid organizational structures; each team uses processes that work the best for its members and projects. You will be working closely with our US teams based in Arlington, VA, New York City, NY, and Pune, India.

This is a hybrid position based in Arlington, VA, requiring three days per week onsite.

Role:
• Lead testing efforts for large, complex product features that support high-impact decision-making for global clients.
• Ensure the accuracy and integrity of calculations and analytics across a variety of scenarios and data conditions.
• Coordinate testing activities across major releases while supporting continuous integration and continuous delivery practices.
• Design, develop, and maintain automated test frameworks and processes to improve testing efficiency and coverage.
• Contribute to delivering an intuitive and high-quality user experience that drives value for customers.
• Collaborate with Product Managers, Engineers, and Customer Experience Designers to understand user needs and validate new features.
• Identify opportunities to improve testing strategies, processes, and overall team efficiency.
• Participate in code reviews, testing strategy discussions, and quality initiatives across teams.
• Continuously explore new tools and technologies to enhance quality engineering capabilities.
• Take ownership of personal development while contributing to the growth and success of the broader team.

All About You:
• Hands on experience as a Software Quality Engineer, Software Engineer in Test, or Test Automation Engineer with hands-on involvement in building and maintaining automated testing solutions.
• Strong understanding of software testing techniques including UI testing, automated testing, and test-driven development approaches.
• Experience working within Agile development environments.
• Proficiency with modern testing and development tools such as Playwright, Git, Jenkins, and CI/CD pipelines.
• Experience working with unit testing frameworks (Java Spring Boot preferred).
• Strong SQL expertise, including validating data, troubleshooting issues, and supporting end-to-end testing across data systems.
• Experience working with PostgreSQL, and familiarity with Snowflake, MixPanel and/or Playwright is a plus.
• Strong analytical and problem-solving skills with the ability to understand system behavior end-to-end.
• High attention to detail and the ability to follow structured testing and validation processes.
• Strong collaboration skills with the ability to work effectively with cross-functional and global teams.
• Excellent written and verbal communication skills, with the ability to clearly explain technical concepts to diverse audiences.
• Bachelor’s degree in Computer Science, Software Engineering, Information Technology, Mathematics, or related field. Equivalent practical experience may also be considered.

This role is not eligible for Mastercard’s work authorization sponsorship. As such, candidates must be eligible to work in the United States, now as well as in the future, without employer sponsorship.

LI-NF1

AI3

Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact [email protected] and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly.

Corporate Security Responsibility

All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must:

• Abide by Mastercard’s security policies and practices;
• Ensure the confidentiality and integrity of the information being accessed;
• Report any suspected information security violation or breach, and
• Complete all periodic mandatory security trainings in accordance with Mastercard’s guidelines.

In line with Mastercard’s total compensation philosophy and assuming that the job will be performed in the US, the successful candidate will be offered a competitive base salary and may be eligible for an annual bonus or commissions depending on the role. The base salary offered may vary depending on multiple factors, including but not limited to location, job-related knowledge, skills, and experience. Mastercard benefits for full time (and certain part time) employees generally include: insurance (including medical, prescription drug, dental, vision, disability, life insurance); flexible spending account and health savings account; paid leaves (including 16 weeks of new parent leave and up to 20 days of bereavement leave); 80 hours of Paid Sick and Safe Time, 25 days of vacation time and 5 personal days, pro-rated based on date of hire; 10 annual paid U.S. observed holidays; 401k with a best-in-class company match; deferred compensation for eligible roles; fitness reimbursement or on-site fitness facilities; eligibility for tuition reimbursement; and many more. Mastercard benefits for interns generally include: 56 hours of Paid Sick and Safe Time; jury duty leave; and on-site fitness facilities in some locations.

Pay Ranges

Arlington, Virginia: $132,000 - $212,000 USD

Our Purpose

Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.

Title and Summary

Principal Software Engineer, Data Architecture

Overview:
Mastercard’s Data & Analytics organization is seeking a visionary Principal Software Engineer, Data Architecture to shape and evolve our global enterprise data architecture. Reporting to the SVP, this role serves as the senior technical authority defining how data is designed, governed, secured, and distributed across Mastercard’s complex, global ecosystem.
You will set the architectural vision for modernizing data platforms across a hybrid cloud and on premises environment, supporting both high throughput batch processing and low latency, real time use cases. Your leadership will enable Mastercard’s “edge everywhere, run anywhere” strategy, allowing products and platforms to deploy data workloads consistently, securely, and at scale across our worldwide footprint.
This role combines deep hands on technical expertise with enterprise influence, enabling Mastercard to unlock the full value of its data while meeting stringent regulatory, resiliency, and performance requirements.

Role:
• Serve as the foundational technical leader for enterprise data architecture, partnering closely with the SVP and senior technology leadership.
• Act as a trusted advisor to C suite and executive stakeholders, translating business strategy into scalable data architecture decisions.
• Define and evolve the global data architecture roadmap across hybrid (cloud + on prem) environments.
• Architect secure, resilient solutions that meet global regulatory and compliance mandates, including GDPR, ISO 20022, and regional data localization requirements.
• Champion Data Mesh principles, treating data as a product with federated ownership, governance, and self service enablement.
• Establish organization wide architecture standards and development best practices through the Data & Analytics Architecture Review Board.
• Lead the modernization of legacy data platforms to cloud native architectures across AWS, Azure, and GCP.
• Drive adoption of modern data technologies, including Databricks, Snowflake, Delta Lake, and streaming platforms.
• Enable both real time and batch analytics use cases to support high availability, mission critical workloads.
• Mentor and influence global engineering teams, fostering a culture of technical excellence, accountability, and thoughtful risk taking.

All About You:
• Proven experience operating as a Principal Engineer or equivalent, leading enterprise scale data architecture or platform strategy.
• Deep expertise designing, building, and operating distributed data systems at global scale.
• Hands on experience with technologies such as Apache Spark, Kafka, Flink, and NiFi.
• Demonstrated success modernizing data platforms using cloud native architectures across AWS, Azure, and/or GCP.
• Experience integrating AI driven capabilities into data platforms, with appropriate governance and guardrails for emerging use cases, including agentic commerce.
• Strong understanding of data governance, security, and regulatory compliance in highly regulated, global environments.
• Proven ability to lead and influence architectural initiatives within Agile, SAFe, or product centric delivery models, partnering effectively with product, engineering, and business stakeholders.
• Demonstrated ability to influence technical and business decisions at all levels, including C-suite stakeholders.
• Strong executive presence with the ability to translate complex architecture concepts into business language.
• Exceptional communication skills, with the ability to articulate complex technical concepts to executive and non technical audiences.
• Strong Decency Quotient (DQ) with a track record of building inclusive, collaborative, high performing teams.
• Bachelor’s degree in Computer Science, Engineering, Data Science, or a related quantitative field, or equivalent practical experience.

This role is not eligible for Mastercard’s work authorization sponsorship. As such, candidates must be eligible to work in the United States, now as well as in the future, without employer sponsorship.

LI-NF1

Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact [email protected] and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly.

Corporate Security Responsibility

All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must:

• Abide by Mastercard’s security policies and practices;
• Ensure the confidentiality and integrity of the information being accessed;
• Report any suspected information security violation or breach, and
• Complete all periodic mandatory security trainings in accordance with Mastercard’s guidelines.

In line with Mastercard’s total compensation philosophy and assuming that the job will be performed in the US, the successful candidate will be offered a competitive base salary and may be eligible for an annual bonus or commissions depending on the role. The base salary offered may vary depending on multiple factors, including but not limited to location, job-related knowledge, skills, and experience. Mastercard benefits for full time (and certain part time) employees generally include: insurance (including medical, prescription drug, dental, vision, disability, life insurance); flexible spending account and health savings account; paid leaves (including 16 weeks of new parent leave and up to 20 days of bereavement leave); 80 hours of Paid Sick and Safe Time, 25 days of vacation time and 5 personal days, pro-rated based on date of hire; 10 annual paid U.S. observed holidays; 401k with a best-in-class company match; deferred compensation for eligible roles; fitness reimbursement or on-site fitness facilities; eligibility for tuition reimbursement; and many more. Mastercard benefits for interns generally include: 56 hours of Paid Sick and Safe Time; jury duty leave; and on-site fitness facilities in some locations.

Pay Ranges

O'Fallon, Missouri: $170,000 - $281,000 USD

Arlington, Virginia: $196,000 - $323,000 USD

New York City, New York: $204,000 - $337,000 USD

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Information Systems Sr. Manager – Technology Regulatory Compliance Lead

Live

What you will do

Let’s do this. Let’s change the world. In this vital role, you will lead the delivery of high-quality, robust, and reliable digital technologies and services within the Technology Organization, ensuring seamless support for business, project, and daily operations. You will be accountable for the computer systems compliance framework of the technology function, ensuring adherence to global regulatory requirements and Amgen procedures.

You will lead the strategy for computer system validation (CSV), regulatory compliance, and inspection readiness for the technology team, proactively driving a culture of quality and continuous compliance. Serving as the Technology Regulatory Compliance Lead, you will ensure alignment with global quality and compliance strategies and maintain a state of constant inspection readiness.

Partnering closely with key stakeholders, you will take full ownership of technology services, driving both project execution and operational excellence. Your focus will be on aligning technology solutions with business needs, continuously optimizing approaches to enhance efficiency, and ensuring reliability, service quality, and sustained compliance for our partners.

As Senior Manager of the Technology Department for ANC, you will report directly to the ANC Site Technology Lead Director. This role serves as a key member of the site’s Technology Leadership Team, driving innovation, operational excellence, quality, compliance, and measurable business impact through strategic technology leadership.

Responsibilities:

• Lead the development and execution of the strategy for computer system validation, regulatory compliance, and sustained inspection readiness for the Technology organization.
• Serve as the Technology Regulatory Inspection Lead, ensuring alignment with global quality and compliance strategies.
• Drive inspection readiness efforts, including playbooks, SME coaching, system documentation, and readiness dashboards.
• Oversee digital platform implementations, ensuring strong planning, resource management, risk mitigation, and financial oversight.
• Manage digital technology services, including validation, compliance, data integrity, and system reliability.
• Design and implement effective support models, including vendor and third-party management with clear accountability.
• Lead cross-functional teams, run key meetings, and present updates to senior leadership.
• Deliver technology solutions that improve efficiency, quality, and business alignment.
• Proactively manage complex, simultaneous projects and resolve challenges effectively.
• Establish performance metrics to drive continuous improvement.
• Ensure successful project delivery and promote operational excellence.
• Mentor team members and serve as subject matter experts.
• Stay current on industry and technology trends and build external networks to benchmark best practices.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of Information Systems/Technology and/or Engineering experience

OR

Master’s degree and 4 years of Information Systems/Technology and/or Engineering experience

OR

Bachelor’s degree and 6 years of Information Systems/Technology and/or Engineering experience

OR

Associate’s degree and 10 years of Information Systems/Technology and/or Engineering experience

OR

High school diploma / GED and 12 years of Information Systems/Technology and/or Engineering experience

Preferred Qualifications:

• Industry Experience Preferred: Prior experience in biotechnology, pharmaceutical, or related regulated industries is strongly preferred.
• Depth knowledge and hand on experience in computer validation, regulatory compliance, inspection readiness.
• Bridge Vision and Execution: Translate operational goals into actionable strategies across manufacturing, laboratory, supply chain, quality, engineering, and technology functions using digital technologies, data, advanced analytics.
• Lead Through Influence and Collaboration: Foster strong cross-functional partnerships to build support for initiatives, energize teams, ensure sustained alignment and focus on business priorities and goals.
• Think Strategically: Anticipate impacts, adapt to change, and make well-reasoned decisions that drive continuous improvement and support business needs.
• Champion Continuous Learning: Stay current with emerging tools and technologies, actively contribute to professional communities, and foster a culture of innovation.
• Drive Problem Solving and Innovation: Apply critical thinking and best practices to proactively resolve complex issues and design effective, scalable solutions.
• Communicate with Clarity: Demonstrate strong verbal, written, and presentation skills to engage stakeholders, senior management and lead teams effectively.
• Decision-Making: Clearly articulates the rationale behind decisions and their potential implications, continuously reflecting on successes and failures to enhance performance and decision-making.
• Adaptive Leadership: Recognizes the need for change and actively participates in technical strategy planning.
• Balance Priorities: Manage multiple initiatives with strong organizational skills, ensuring alignment with team goals and measurable performance outcomes.

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and bi-annual company-wide shutdowns
• Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

.

Salary Range

147,259.00 USD - 174,934.00 USD

Career Category

Engineering

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX batch facility will combine the latest in disposable technologies with traditional stainless steel equipment to allow for maximum flexibility in operations The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

Manufacturing Systems Engineer: Automation - PLC

What you will do

Let’s do this. Let’s change the world. As a Manufacturing Systems Engineer, you will work with a group of automation engineers who are responsible for building and maintaining various automation systems and platforms that support the GMP Drug Substance Plant Operations.

In this vital role as a member of the Facilities & Engineering (F&E) Automation team you will work hand in hand with the capital project team to deliver robust automation systems to operate the new plant utility and standalone systems. This includes sophisticated and challenging system automation initiatives that require understanding of various automation platforms, integration between different platforms, analytical problem-solving techniques, project management, lifecycle management and Operational Excellence.

• Develop and maintain automation solutions using various PLC's such as Allen Bradley, Siemens, etc. and integration with the Emerson DeltaV system.
• Develop and maintain Supervisory Control and Data Acquisition system (SCADA), Trailblazer reporting system, and equipment PLC’s and interface hardware.
• Support standalone system implementation and start-up, participate and provide technical guidance in the control panel / Human Machine Interfaces (HMI) layout and design including power distribution, grounding requirements, I/O assignments, etc.
• Work with process subject matter experts (SMEs) to understand key process requirements and transform them into digital automated solutions.
• Assist in continuous improvement and innovation initiatives for efficient operation and sustainability improvements of standalone systems.
• Collaborate with business partners to understand how standalone systems can improve workflow and productivity. Synthesize requirements from clients, customers, or end-users to develop the best automation solutions.
• Provide clear documentation for delivered solutions and processes; work closely with QA partners while supporting computerized systems validation processes in a GxP environment. Maintain Data Integrity Assessments with the current Amgen and Industry standards.
• Build the business processes to support the project scope in alignment with project timelines. Develop detailed specification and engineering policies and procedures that affect multiple organizational units.

Ongoing operations:

• Support functional area projects focused on improving process equipment/utilities/facilities as well as large/sophisticated capital projects to integrate new drug substance manufacturing technologies into the facility.
• Support technical root cause analysis, incident investigations, and troubleshooting on standalone systems.
• Support new product introductions (NPI) or new technology introductions by performing automation engineering assessments, implementing automation system configuration changes, and supporting engineering and process qualification runs as applicable.
• Assist with Day-to-Day Operational Support including: 24 x 7 Onsite/On Call Operational Support, Troubleshooting Support to Standalone Systems, Preventative and Corrective Maintenance, and Automation System spare parts management.
• Be constantly curious and feed your passion and interests in groundbreaking technology. Use your given time to look for new and innovative ways to do business differently, better, and more cost effectively.

What we expect of you!

We are all different, yet we all use our unique contributions to serve patients. The automation professional we seek is an engineer with these qualifications.

Basic Qualifications:

• High School Diploma / GED and 8 years of Engineering experience OR
• Associate’s Degree and 6 years of Engineering experience OR
• Bachelor’s Degree and 2 years of Engineering experience OR
• Master’s Degree

Preferred Qualifications:

• Degree in Electrical Engineering or Computer Science, Chemical Engineering, or Biotech Engineering.
• Direct knowledge of PLC design, experience in controls engineering and troubleshooting with GMP biopharmaceutical production facility and utility equipment/systems automation such as autoclaves, parts washers, clean steam generator, WFI pretreatment RO, WFI stills, filter integrity testers, wastewater treatment systems, and integrating various OEM automation software.
• Extensive understanding and background in programming, design, installation, and lifecycle management of standalone controls, PLC, and field device/instrumentation technologies.
• Experience with Rockwell industrial automation hardware and systems, ability to perform sophisticated troubleshooting activities, System Integration using OPC, Foundation Fieldbus, Profibus, and DeviceNet technologies.
• Ability to interpret and apply GAMPs and GMPs and familiarity with documentation in a highly regulated environment with requirements such as 21 CFR Part 11, ASTM 2500, S88, and S95.
• Experience in Capital Project Lifecycle Management: Conceptual Design, Scope and cost estimate development, business case development, detailed design, engineering and validation documentation and project execution.
• Hands-on experience in developing process control strategies for New Product Introduction and New Technology Deployment for Drug Substance Plant Operations.
• Experience with continuous improvements resulting in enhanced safety, system reliability, and productivity (e.g., cycle times, and reduced plant utilities usage etc.) related to Drug Substance Plant Operations.
• The ideal individual must be a self-directed great teammate ready to embrace a team-based culture that relies on collaboration for effective decision-making.
• Strong technical writing and communication/presentation skills.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Apply now and make a lasting impact with the Amgen team!

careers.amgen.com

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

.

Salary Range

118,497.00 USD - 134,250.00 USD

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Manufacturing Systems Engineer – Manufacturing Systems and Integrated Technologies

What you will do

Let’s do this. Let’s change the world. In this vital role, you will be a part of our Clinical and Commercial Manufacturing Operations Technology team, driving the operation, refinement, and integration of cutting-edge manufacturing applications. This role is an excellent opportunity to gain an understanding of Amgen’s key manufacturing systems, working with various MCS (Manufacturing and Clinical Supply) business partners to ensure products to patients by managing and supporting key computerized systems such as MES (Manufacturing Execution System), Clinical Label Printing and Packaging, PI Data Historian, Instrument Data Acquisition (IDA) and other integrated systems.

As a member of our team, you'll be the driving force behind our mission to deliver high-quality products efficiently and effectively. This role will be responsible for managing the MES platform and associated integrations for the ATO site. In addition to supporting key manufacturing operations, you will work closely with the Global Instrument Data Acquisition (IDA) team to drive a Global MES Standardization effort across all Amgen manufacturing locations. This includes ensuring seamless integration of instrument data, implementing standardized MES processes and protocols, and collaborating with global stakeholders to align best practices and compliance requirements. Your efforts will be critical in optimizing manufacturing systems, enhancing data integrity, and promoting consistency and efficiency across Amgen’s worldwide network.

You'll collaborate closely with cross-functional teams, site business leads and plant leads that include Manufacturing, Supply Chain, Quality, MCS Engineering, Enterprise Architects, and MES/IDA Global Teams to ensure seamless implementation and optimization of MES, PI Historian Systems, and support partnering with MCS automation/engineering teams for GLAM project support.

The role will be part of the Site Operations Technology team which is responsible for delivering systems in support of Clinical and Commercial Manufacturing, working in a client facing ATO site- focused approach.

Responsibilities:

• Support key TCT manufacturing systems by driving operational stability and continuous improvements across Building 7, B20, B23, and the ATO site.
• Manage key system integrations, both existing and new, to streamline manufacturing operations.
• Champion business process improvements and support strategic digital initiatives by leveraging established platforms, city plan technology, and artificial intelligence applications.
• Provide on-call support, including after-hours escalations and troubleshooting for operations technology application issues, aligned with 24x7 manufacturing requirements at the ATO site.
• Lead major incident and problem investigations, including root cause analysis, deviation investigations, corrective actions, and 5-why analysis.
• Ensure compliance by maintaining and updating inspection readiness for critical applications, including inspection playbooks, periodic assessments for data integrity, security, and system compliance, and SDLC validation and testing.
• Support regulatory inspections by providing data, delivering presentations on site systems and technology processes, and collaborating with subject matter experts as needed.
• Lead initiatives to introduce Industry 4.0 technologies to improve manufacturing efficiency and capacity.
• Lead and train team members to support operational excellence and develop multi-system competencies.
• Support and lead CMDB updates and system health, ensuring accurate and up-to-date configuration data in partnership with service owners and managers.
• Support the assessment of impactful changes during weekly ATO Change Advisory Board (CAB) meetings.
• Support Amgen’s cyber resiliency efforts, including Sentinels and ECR Network initiatives.
• Provide on-site, client-facing support at the ATO site up to five days per week, based on business needs.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree

OR

Master’s degree and 2 years of Information Systems/Systems Engineering experience

OR

Bachelor’s degree and 4 years of Information Systems/Systems Engineering experience

OR

Associate’s degree and 8 years of Information Systems/Systems Engineering experience

OR

High school diploma / GED and 10 years of Information Systems/Systems Engineering experience

Preferred Qualifications:

• BS/MS degree in Information Systems, Computer Science, Engineering, or the Life Sciences.
• 5+ years’ experience in the biotech/pharmaceutical industry and working with GxP computer systems in a regulated environment.
• Experience with Amgen Technology Systems support and validation.
• Database skills (queries, stored procedures, reports).
• Experience with CDOCS, Application Lifecycle Management (ALM).
• Strong history of analytical and troubleshooting skills.
• Experience with ISM/AmgenNow is preferred.
• Work experience within biotechnology, pharmaceutical, or healthcare.
• Strong leadership/consultative, collaboration, project management, service delivery, and process improvement skills to facilitate alignment across multiple stakeholder groups.
• Strong experience in systems analysis. Ability to work with business clients to understand their business processes, manage scope of work/expectations, and suggest/recommend IS solutions.
• Experience leading the IS change control process and building, validating, and supporting GxP systems.
• Strong written, presentation, and verbal communication skills and technical expertise to be able to communicate effectively with business and technology partners.
• Organization, with proven ability to quickly learn new concepts and technologies and prioritize outcomes.
• Experience in technical writing and performing root cause analysis of incidents/deviations and handling CAPA.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

.

Salary Range

147,421.00 USD - 177,467.00 USD

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Specialist Scientific IS Business Analyst

What you will do

Let’s do this. Let’s change the world. In this vital role, you will work closely with Amgen Research partners and Technology peers to ensure that the technology/data needs for drug discovery research are translated into technical requirements for solution implementation. The role leverages scientific domain and business process expertise to detail product requirements as epics and user stories, along with supporting artifacts like business process maps, use cases, and test plans for the software development teams. This enables the delivery team to estimate, plan, and commit to delivery with high confidence and identify test cases and scenarios to ensure the quality and performance of IT Systems.

You will join a multi-functional team of scientists and software professionals that enables technology and data capabilities to evaluate drug candidates and assess their abilities to affect the biology of drug targets. This team implements software and infrastructure that enables the capture, processing, storage, analysis and reporting of pre-clinical and clinical omics (genomics, proteomics, transcriptomics, epigenomics etc.) data. In addition, this role works closely with In Vivo – biological studies team to support lead optimization studies.

You will collaborate with Product Owners and developers to maintain an efficient and consistent process, ensuring quality deliverables from the team. You will implement and manage scientific software platforms across the research informatics ecosystem, and provide technical support, training, and infrastructure management, and ensure it meets the needs of our Amgen Research community. This role also entails understanding business needs for AI enabled solutions and facilitating building of data connectors to various data sources.

Roles & Responsibilities:

• Function as a Scientific Business Systems Analyst within a Scaled Agile Framework (SAFe) product team.
• Serve as a liaison between global Research Informatics functional areas and global research scientists, prioritizing their needs and expectations.
• Manage a suite of custom internal platforms, commercial off-the-shelf (COTS) software, and systems integrations.
• Translate complex scientific and technological needs into clear, actionable requirements for development teams.
• Stay updated with industry trends, technological advancements, and scientific progress in Omics techniques and advances in imaging techniques (e.g. Radiomics, cell painting, high content cell-based imaging), including data generation, processing, and analysis.
• Develop and maintain a product roadmap that clearly outlines planned features and enhancements, timelines, and milestones.
• Identify and manage risks associated with the systems, including technological risks, scientific validation, and user acceptance.
• Develop documentation, communication plans, and training plans for end users.
• Ensure scientific data operations are scoped into building research-wide Artificial Intelligence and Machine Learning capabilities.
• Ensure operational excellence, cybersecurity, and compliance.
• Collaborate with geographically dispersed teams, including those in North America and other international locations.
• Foster a culture of collaboration, innovation, and continuous improvement.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree

OR

Master’s degree and 2 years of Life Sciences, Computer Science, IT, Computational Biology/Bioinformatics or related field

OR

Bachelor’s degree and 4 years of Life Sciences, Computer Science, IT, Computational Biology/Bioinformatics or related field

OR

Associate’s degree and 8 years of Life Sciences, Computer Science, IT, Computational Biology/Bioinformatics or related field

OR

High school diploma / GED and 10 years of Life Sciences, Computer Science, IT, Computational Biology/Bioinformatics or related field

Preferred Qualifications:

• 4+ years of experience in implementing and supporting biopharma scientific software platforms along with understanding of research in vivo studies and data analytics.

**Functional Skills:

Must-Have Skills:**

• Expertise in Omics data management and analysis (Genomics, Proteomics, Transcriptomics etc.) including understanding of disease biology.
• Experience with bioinformatics tools and research workflows used to manage omics data.
• Knowledge of in vivo research workflows, study data, experimental metadata and analytics.
• Familiarity with research imaging modalities, techniques and analytics.
• Good understanding of database technology (e.g. RDBMS, Databricks).

Good-to-Have Skills:

• Experience with writing user requirements and acceptance criteria in agile project management systems such as JIRA.
• Knowledge of handling GxP data and system validation (i.e. GCP).
• Understanding of AI and machine learning for drug discovery research and preclinical development.
• Exposure to radiomics or high-content imaging.
• Familiarity with AI/ML-based imaging analysis pipelines.
• In-depth knowledge of Agile processes and principles for coordinated solutions and teams via SAFe.
• Experience managing vendors, licenses in support of a Product team.
• Knowledge of business analysis best practices, DevOps, Continuous Integration, and Continuous Delivery methodology.
• Experience with platforms such as Benchling, or other LIMS.
• Understanding of cloud technologies, pipelines, and data storage.

Professional Certifications:

• SAFe for Teams certification (preferred).

Soft Skills:

• Able to work under minimal supervision.
• Excellent analytical and gap/fit assessment skills.
• Strong verbal and written communication skills.
• Ability to work effectively with global, virtual teams.
• High degree of initiative and self-motivation.
• Ability to manage multiple priorities successfully.
• Team-oriented, with a focus on achieving team goals.
• Strong presentation and public speaking skills.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

.

Salary Range

110,038.45USD -148,875.55 USD

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Principal Data Scientist - Forecasting

What you will do

We are seeking a Principal Data Scientist - Forecasting to join the Forecasting team, within the AI & Data organization. This role will lead the development of advanced statistical, Bayesian, causal, and machine learning models that improve forecasting capabilities and quantify uncertainty to guide strategic decision making across the company.

This leader will partner across Commercial, Operations, Supply Chain, Manufacturing, Finance, and Technology to build forecasting technology that support critical business processes, ensuring Amgen delivers on its “every patient, every time” mandate. The role is particularly suited to a creative problem solver who is excited about leveraging state of the art forecasting methods, complex high-dimensional data sources, and agentic development practices to build decision-support tools that connect demand signals with supply constraints, enabling reliable, risk-adjusted scenario planning across short-, mid-, and long-range horizons.

Key Responsibilities

• Develop advanced statistical, Bayesian, and machine learning models to forecast demand across multiple horizons, including near-, medium-, and long-term planning horizons.
• Work with large, complex data sets, leveraging state of the art techniques in statistical modeling, causal inference and analytics to generate insights that support strategic decision making across the business.
• Develop high fidelity simulation and scenario evaluation capabilities to understand the complex dynamics between patients, payers and providers.
• Own the end-to-end modeling lifecycle, including scoping, prototyping, data analysis, feature engineering, model development, deployment and, monitoring as well as explainability.
• Architect and develop self-service forecasting tools and platforms, ensuring leadership can act on near real-time predictions.
• Collaborate with cross functional teams in Commercial, Operation, Finance and Technology to ensure forecasts are well integrated into critical business workflows.
• Develop a holistic understanding of Amgen’s systems and processes in relation to industry challenges and broader trends to identify opportunities and risks.
• Research and evaluate emerging tools and methodologies in forecasting, data science and AI.
• Establish forecasting as an advanced, rigorous practice across the organization and upskill and mentor junior team members.

Basic Qualifications

• Doctorate degree and 2 years of data science in enterprise environments experience OR
• Master’s degree and 4 years of data science in enterprise environments experience OR
• Bachelor’s degree and 6 years of data science in enterprise environments experience OR
• Associate’s degree and 10 years of data science in enterprise environments experience OR
• High school diploma / GED and 12 years of data science in enterprise environments experience

Preferred Qualifications

• 8+ years of experience applying data science in enterprise environments with demonstrated principal-level influence or equivalent depth of expertise.
• Deep expertise in time-series forecasting, probabilistic programming, Bayesian and predictive modeling, with practical experience delivering models that drive business measurable value.
• Expert understanding of Python, SQL and tools such as scikit-learn, PyMC, Pytorch, Tensorflow and other data science libraries.
• Strong communication and story-telling skills, with ability to explain complex technical concepts and influence executive level decision making.
• Exceptional stakeholder management with ability to drive alignment on, relationships, and metrics, and communicate tradeoffs clearly.
• An intellectually curious self-starter who can take ambiguous problems and build robust solutions from 0 to 1.
• Experience building and scaling forecasting platforms for biotech/pharma use cases and knowledge of healthcare commercial concepts such as payer/provider dynamics, formulary access, and coverage.
• Experience leveraging machine learning, operations research algorithms, and statistical modeling for retail, consumer goods, supply chain or manufacturing applications
• Deep expertise in causal inference, Bayesian forecasting, and hierarchical or multi-level forecasting methods.
• Familiarity with ML Ops, CI/CD, and engineering best practices that enable scalable deployment and adoption of forecasting products.

What You Can Expect Of Us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now for a career that defies imagination

Objects in your future are closer than they appear. Join us.
careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

.

Salary Range

160,896.50USD -217,683.50 USD

Career Category Information Systems Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Data Scientist - Forecasting What You Will Do We are seeking a Data Scientist, Forecasting to join the Forecasting team within the AI & Data organization. This role will support the development of statistical, Bayesian, causal, and machine learning models that enhance forecasting capabilities and quantify uncertainty to guide decision-making across the company. This role will work cross-functionally to help build forecasting solutions that support critical business processes and contribute to Amgen’s “every patient, every time” mandate. The position is well suited to a curious and collaborative problem solver who is excited about applying forecasting methods, complex datasets, and modern analytical tools to build decision-support solutions that inform planning and business decision-making. Key Responsibilities Develop and refine statistical, Bayesian, and machine learning models to support demand forecasting across near-, medium-, and long-term planning horizons. Analyze large, complex datasets using statistical modeling, forecasting, and analytics techniques to generate insights that support business decision-making. Support the development of simulation and scenario-analysis capabilities to better understand dynamics among patients, payers, providers, and market conditions. Contribute across the modeling lifecycle, including business problem framing, exploratory data analysis, feature engineering, model development, validation, deployment support, monitoring, and explainability. Collaborate with senior team members to evaluate and apply new tools and methodologies in forecasting, data science, and AI to business problems. Communicate analytical findings and model results clearly to technical and non-technical stakeholders. Basic Qualifications Master’s degree OR Bachelor’s degree and 2 years of applying data science, analytics, or statistical modeling in industry, research, or enterprise environments experience OR Associate’s degree and 6 years of applying data science, analytics, or statistical modeling in industry, research, or enterprise environments experience OR High school diploma / GED and 8 years of applying data science, analytics, or statistical modeling in industry, research, or enterprise environments experience Preferred Qualifications 2+ years of experience applying data science, analytics, or statistical modeling in industry, research, or enterprise environments. Experience with time-series forecasting, predictive modeling, or related quantitative methods. Proficiency in Python and SQL, with experience using tools such as scikit-learn, PyMC, PyTorch, TensorFlow, or similar data science libraries. Solid analytical and statistical foundation, with the ability to work with messy and complex datasets to generate actionable insights. Familiarity with model development workflows, including data preparation, feature engineering, evaluation, and interpretation. Strong communication skills, with the ability to explain technical concepts and results to a rapplying data science, analytics, or statistical modeling in industry, research, or enterprise environments. Strong collaboration skills and ability to work effectively in cross-functional environments. Intellectual curiosity and a willingness to learn, take on ambiguous problems, and grow in a fast-paced environment Experience applying machine learning, statistical modeling, or decision science methods in retail, consumer goods, supply chain, manufacturing, or similar settings. Exposure to causal inference, probabilistic modeling, or scenario analysis is a plus. What You Can Expect Of Us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. . Salary Range 103,852.15USD -140,505.85 USD Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.

Position Summary:

As a Manager - Systems Engineering, you will be responsible for automating, optimizing, and modernizing virtualization environments for Enterprise Managed File Transfer infrastructure. This System Engineer will ensure the reliability, performance, optimization, and security of CVS Health's MFT Infrastructure systems. The MFT infrastructure spans over multiple datacenters and virtual environments. The enterprise MFT infrastructures use several technologies by vendors like Axway and IBM.

Required Qualifications:

• 5+ years of operational experience with IBM Sterling Suite (Sterling Integrator, Sterling File Gateway, MQ, ITX/WTX, ITXA, IBM Control Center, Sterling Secure Proxy, Secure External Authentication Server)
• 3+ years of programming experience (Perl, SQL, Unix script, Python, JAVA, PHP)

Preferred Qualifications:

• Operational experience with Axway Secure Transport
• Knowledge of cloud technologies (AWS, GCP, Azure)
• Knowledge of AI integrations
• Red Hat Linux
• Operational experience with Axway Secure Transport
• Experience in DevOps principles, automation strategies, and advanced container orchestration, with a understanding of tools such as Kubernetes
• Strong scripting and automation skills, enabling the creation of robust and efficient automation solutions
• Familiarity with security and compliance standards, such as HIPAA and NIST, ensuring adherence to industry best practices and regulatory requirements
• Experience and knowledge of additional MFT technologies like GoAnywhere, Seeburger, Ipswitch

Education:

• Bachelor’s degree, or equivalent experience (HS diploma + 4 years relevant experience)

Anticipated Weekly Hours

40

Time Type

Full time

Pay Range

The typical pay range for this role is:

$44.57 - $89.14

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls.  The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors.  This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above. 

Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.

Great benefits for great people

We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.

This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.

Additional details about available benefits are provided during the application process and on Benefits Moments.

We anticipate the application window for this opening will close on: 04/30/2026

Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.

Position Summary

The Vice President, Cyber Defense & Threat Intelligence is a senior executive responsible for designing, building, and operating CVS Health's global defensive cyber capability. This leader commands the enterprise Security Operations Center (SOC), Computer Security Incident Response Team (CSIRT), Cyber Threat Intelligence (CTI) program, Insider Risk Operations, Artificial Intelligence Security Operations (AI SecOps), Security Data Analytics, Penetration Testing, Red/Blue Team operations, and Crisis Incident Response — A unified platform protecting one of the nation's largest healthcare enterprises and the sensitive personal health information of more than 180 million Americans.

Reporting directly to the CISO, this role is the company's senior operational defender and primary technical authority during significant cyber events. The VP operates within CVS Health's CISO leadership team and will build a culture of precision, speed, and mission orientation across a multi-disciplinary team, translating intelligence into prevention and detection while ensuring that operational outcomes meet the expectations of regulators, the Board, and executive leadership.

Key Responsibilities

Security Operations Center (SOC)

• Own 24x7x365 enterprise SOC operations, ensuring continuous monitoring, detection, and triage across on-premises, cloud, and hybrid environments.
• Drive SOC maturity through automation, SOAR playbook development, and metrics-driven performance management — targeting measurable reductions in mean time to detect (MTTD) and mean time to respond (MTTR).
• Ensure SOC staffing, tooling, and process design meets HIPAA, PCI-DSS, and applicable state regulatory expectations for continuous monitoring of PHI/PII environments.
• Lead vendor and MSSP relationships supporting SOC augmentation, establishing clear SLAs and escalation protocols.

​Cyber Threat Intelligence (CTI)

• Establish and mature an enterprise CTI program that delivers operationally relevant, decision-ready intelligence to executive, technical, and legal stakeholders.
• Maintain active participation in sector-specific intelligence sharing communities (H-ISAC, FS-ISAC where applicable) and government partnerships (CISA, FBI, HHS/OCR).
• Develop geopolitical and nation-state threat awareness programs that inform executive decision-making and enterprise risk posture.
• Integrate CTI feeds directly into SOC detection logic, vulnerability prioritization, and red team planning.

Computer Security Incident Response Team (CSIRT)

• Lead CSIRT operations responsible for classification, investigation, containment, eradication, and recovery of all significant security events.
• Own incident response plans, runbooks, and tabletop exercise programs — ensuring alignment with legal counsel, privacy, compliance, and communications teams.
• Serve as primary technical authority for all Severity 1 and Severity 2 security incidents; ensure appropriate executive and regulatory notification in accordance with applicable breach notification laws (HIPAA, state data breach statutes, SEC cybersecurity disclosure rules).
• Maintain chain-of-custody and forensic evidence standards that support potential litigation, regulatory investigation, or law enforcement cooperation

Insider Risk Operations

• Build and operate a formal Insider Risk program capable of detecting, investigating, and responding to malicious, negligent, and compromised insider threats at enterprise scale.
• Partner with Human Resources, Legal, and Employee Relations to ensure insider risk investigations are legally defensible, appropriately scoped, and compliant with applicable employment law and privacy regulations.
• Design behavioral analytics and UBA/UEBA detection capabilities that distinguish anomalous from malicious activity while minimizing employee privacy intrusions.
• Develop escalation protocols for referral of insider cases to law enforcement or legal action where appropriate.

Artificial Intelligence Security Operations (AI SecOps)

• Establish CVS Health's enterprise AI Security Operations function — responsible for monitoring, detecting, and responding to threats targeting AI/ML systems, LLMs, agentic workflows, and AI-powered business processes.
• Develop detection and response capabilities for emerging AI threat vectors including prompt injection, model extraction, adversarial inputs, training data poisoning, and AI supply chain risk.
• Partner with the Enterprise AI Platform team to embed security monitoring into AI pipelines, model governance workflows, and API integrations.
• Develop and publish AI security incident response playbooks specific to healthcare regulatory context and PHI exposure risk.

Security Data Analytics & SIEM/SOAR Engineering

• Own the enterprise security data platform — including SIEM architecture, data lake engineering, telemetry ingestion pipelines, and security analytics — ensuring full visibility across the environment.
• Lead development of advanced detection analytics, behavioral models, and machine learning-assisted threat hunting capabilities.
• Establish and maintain security data governance standards, ensuring log retention, integrity, and availability consistent with legal hold, regulatory, and forensic requirements.

Drive measurable improvement in detection fidelity — reducing false positive rates while increasing signal quality across all detection layers.

Penetration Testing

• Manage the enterprise penetration testing program — including internal assessments, application testing, red team operations, and third-party engagements — on a risk-prioritized schedule.
• Ensure testing scope covers traditional infrastructure, cloud-native environments, AI/ML systems, mobile applications, API surfaces, and physical security where relevant.
• Drive clear, actionable reporting of findings to technical owners and executive leadership, with tracked remediation metrics.
• Maintain compliance with regulatory testing requirements (e.g., PCI-DSS penetration testing mandates, HIPAA technical safeguard assessments).

Adversarial Operations

• Lead a mature adversary simulation program that continuously stress-tests CVS Health's detection and response capability against real-world threat actor TTPs, including nation-state and financially motivated adversaries.
• Operate Purple Team exercises that close the loop between red team findings and blue team detection improvements — with documented, measurable outcomes.
• Ensure red team operations are appropriately scoped, legally authorized, and operationally deconflicted with SOC to avoid unintended disruption.
• Leverage MITRE ATT&CK framework as the common language for adversary emulation, detection coverage assessment, and security control validation.

Incident Crisis Response & Executive Communication

• Serve as the senior operational executive during declared cyber crises — coordinating technical response, legal liaison, executive briefings, and regulatory notification timelines in close collaboration with the SVP, Deputy CISO and other CISO leadership team members.
• Develop and maintain the enterprise Cyber Crisis Management Plan in coordination with Enterprise Risk Management, Legal, Communications, and Board-level stakeholders.
• Own communications to the CISO, SVP, CFO, CEO, Board Audit Committee, and external regulators during significant incidents — ensuring precision, legal accuracy, and appropriate confidentiality.
• Lead post-incident review processes that produce legally defensible records, root cause analysis, and measurable control improvements.

Leadership & Organizational Responsibilities

• Recruit, develop, and retain a high-performing, diverse team of cyber defense professionals across SOC, CSIRT, threat intelligence, and offensive/defensive security disciplines.
• Establish a culture of continuous improvement, threat-informed defense, and mission orientation that operates effectively under pressure.
• Develop annual operating budgets, headcount plans, and vendor strategy for all functions within scope; present business cases for investment with clear ROI framing.
• Represent cyber defense operations in executive forums, Board presentations, regulatory examinations, and external audits.
• Partner with the CISO and SVP, Deputy CISO on enterprise security strategy, architecture, and policy

— ensuring all cyber defense operations are aligned with enterprise-wide security direction and that the VP's functional scope is clearly delineated from adjacent leadership mandates.

• Serve as a visible external representative of CVS Health's security posture through industry conferences, regulatory engagement, and peer collaboration.

Required

• 15+ years of progressive cybersecurity leadership experience, with a minimum of 8 years in senior leadership roles overseeing enterprise-scale security operations.
• Demonstrated experience leading or significantly maturing a 24x7 SOC, CSIRT, and/or threat intelligence function in a large, complex enterprise environment.
• Proven track record of leading significant cyber incident response events — including ransomware, nation-state, and insider threat scenarios — at enterprise scale.
• Deep technical fluency across core cyber defense domains: SIEM/SOAR, endpoint detection and response (EDR), network security monitoring, cloud security monitoring (AWS, Azure, GCP), and threat intelligence platforms.
• Strong executive communication skills — able to translate complex technical findings into precise, actionable, and legally defensible communications for C-suite and Board audiences.
• Experience operating in highly regulated industries with significant personal data obligations (healthcare, financial services, retail, or equivalent).
• Familiarity with HIPAA Security Rule, NIST CSF, NIST SP 800-53, CIS Controls, MITRE ATT&CK, and applicable state data breach notification laws.
• Experience leading insider risk or behavioral analytics programs with appropriate HR/Legal partnership.

Preferred

• Healthcare industry experience with direct exposure to HIPAA/HITECH compliance, OCR investigation response, and healthcare-specific threat actor activity.
• Experience building or maturing AI/ML security operations capabilities — including detection of prompt injection, adversarial ML, and AI supply chain risk.
• Background in red team or offensive security operations (OSCP, GXPN, or equivalent).
• Legal or compliance background, or demonstrated experience working closely with legal counsel in incident response, regulatory notification, and litigation support contexts.
• Experience testifying before regulatory bodies, law enforcement, or legislative committees.
• Prior experience at CISO level or as a direct CISO report in a Fortune 50 or equivalent organization

Certifications (Preferred)

CISSP

CISM

GCIA / GCIH / GREM

GCFE / GCFA (Forensics)

OSCP / GXPN (Offensive)

AWS/Azure/GCP Security Specialty

SANS GSOM / GSE

CISA

Pay Range

The typical pay range for this role is:

$0.00 - $0.00

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls.  The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors.  This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above.  This position also includes an award target in the company’s equity award program. 

Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.

Great benefits for great people

We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.

This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.

Additional details about available benefits are provided during the application process and on Benefits Moments.

We anticipate the application window for this opening will close on: 05/11/2026

Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.