Principal Software Engineer

Regeneron

Quick summary

Work type
On-site
Location
Tarrytown
Salary
$128,600–$210,000 / yr
Posted
81 days ago

Market check

Salary context

Competitive pay

How this pay compares to similar roles

Similar $188k
This role $169k
$116k most similar roles pay here $246k

This role pays less than 62% of similar roles. Most pay $161,500–$214,500 — the shaded band above. At the midpoint, this role pays about $169k versus about $188k for comparable roles.

Based on 240 similar postings.

Employer

About Regeneron

Regeneron is a leading science-driven biotechnology company that invents, develops, and commercializes life-transforming medicines for serious diseases.

Regeneron currently has 20 open roles on FindRole.

Listed pay typically runs $131,500–$230,200 across 20 roles with salary data.

Most-posted roles

View all roles at Regeneron

At a glance

TL;DR · Principal Software Engineer

As a Principal Software Engineer at the Regeneron Genetics Center, you will join a forward-thinking IT team that builds and maintains critical platform tooling and APIs used by research teams to analyze large-scale genetic data. Your day-to-day responsibilities include developing cloud-based data pipelines on AWS, integrating AI tools like Claude Code into development workflows, and collaborating with scientists to deliver robust solutions for scientific discovery. You will need strong experience in API design, RESTful services, and microservices architecture, along with hands-on expertise in Python, TypeScript, Docker, and AWS services. Additionally, familiarity with databases such as PostgreSQL or MySQL, ETL orchestration tools, and AI/ML service integration is essential. This role requires a deep understanding of cloud-native development and the ability to work collaboratively in a high-impact environment focused on advancing genetic research at scale.

What you'll do

  • Develop APIs and services for accessing large-scale genetic data used by research teams.
  • Design and maintain cloud-based data pipelines on AWS to handle high-volume genomic data efficiently.
  • Integrate AI tools into development workflows to enhance coding efficiency and solution quality.
  • Collaborate with scientists and engineers to deliver technical solutions that improve scientific discovery processes.
  • Ensure the reliability and performance of shared platform tooling used by research teams.

What we're looking for

  • At least 6 years of experience building cloud-native applications
  • Strong background in API design and development using REST patterns
  • Hands-on experience with AI/ML service integration and LLM-assisted tools
  • Expertise in AWS cloud services and Docker for infrastructure management
  • Proficiency in Python, TypeScript, and data pipeline orchestration
  • Experience working collaboratively in a team environment on complex projects
  • Commitment to delivering high-quality solutions that are testable and maintainable

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